Acne vulgaris is the most frequent primary diagnosis reported by dermatologists.1 To some degree, it affects nearly all adolescents, presenting as comedones, papules and pustules and in severe cases nodules…

I read with great interest the recent article by Huang et al,1 bexarotene (BEX) may also have potent benefits for the treatment of various neurological disorders. For instance, recent data…

The incidence of non-melanoma skin cancers (NMSCs) has been dramatically increasing, with basal cell carcinomas (BCCs) accounting for about 80% of the tumors.1 In the last decade, huge efforts have…

INTRODUCTION The impairment of the health related quality of life (HRQoL) caused by psoriasis can be compared to other severe diseases such as ischemic heart disease, chronic obstructive pulmonary disease,…

INTRODUCTIONPsoriasis is a common, lifelong, immune-mediated genetic disease, resulting in a substantial physical and emotional burden. In psoriasis, an activated cytokine network stimulates a cycle of ongoing inflammation and cellular…

INTRODUCTIONTopical corticosteroids (TC) are commonly regarded as a mainstay of AD therapy. However, there exist several problems including topical steroid addiction (TSA) or Red burning skin syndrome.1,2 There are a…

INTRODUCTIONDespite its ubiquity, a single definition for “sensitive skin” remains elusive and there is little agreement among dermatologists beyond heightened sensitivity on its symptomatology.1 Most of the research data currently…

INTRODUCTION Patients with heavily sun-damaged skin frequently have a substantial burden of actinic keratosis (AK) and subclinical AKs that are commonly treated with topical therapy to target large areas. Although…

INTRODUCTIONNon-melanoma skin cancers (NMSC) are the most common cancer worldwide and pose a significant and increasing burden on health care resources, with an estimated cost of $650 million and 2,200…

INTRODUCTIONMelanoma is a deadly skin cancer, killing more than 9,000 Americans in 2012. Incidence is rising rapidly, to the point where 1 in 50 Americans will develop melanoma.1 Stage at…

INTRODUCTIONInjectable poly-L-lactic acid (PLLA) is a biodegradable, biocompatible, synthetic polymer that acts as a scaffold to promote collagen formation.1 It is FDA-approved for the correction of facial lipoatrophy in patients…

INTRODUCTIONExcessive fat is not only cosmetic but also an overall health problem. People who exceed their ideal body weight by more than 20% have an increased risk of type 2…