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Dec 10
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Sign and Pseudo-Sign of Leser-Trelat

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Recently, a paper of Husain et al.1 was published in the JDD about sign and pseudo-sign of Leser-Trélat. To our understanding, the authors misunderstood the nature of the pseudo-sign of…
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Dec 10
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The Phototoxic and Photoallergy Potential of Clindamycin Phosphate 1.2%/ Tretinoin 0.025% Gel for Facial Acne: Results of Two Single-Center, Evaluator-Blinded, Randomized, Vehicle-Controlled Phase 1 Studies in Healthy Volunteers

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INTRODUCTION The FDA recommends photosafety testing for topical drug products that absorb light in the range of 290nm to 700nm that will be applied to sun-exposed skin.1 For topical products…
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Dec 10
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Recent Trend in the Choice of Fillers and Injection Techniques in Asia: A Questionnaire Study Based on Expert Opinion

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INTRODUCTIONFacial fillers, injectable therapeutic materials for soft tissue augmentation, are ideal for restoring facial volume and contour.1 With recognition of its value, as well as the ease of office procedures…
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Dec 10
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A Randomized, Multicenter, Double-Blind, Vehicle-Controlled Study Evaluating the Efficacy and Safety of Luliconazole Cream 1% Once Daily for 7 Days in Patients Aged ≥ 12 Years With Tinea Cruris

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INTRODUCTION Tinea cruris, a pruritic, superficial fungal infection of the groin and adjacent skin, is the second most common clinical presentation of dermatophytosis. It affects the upper inner thighs and…
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Dec 10
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A Novel, Volumizing Cosmetic Formulation Significantly Improves the Appearance of Target Glabellar Lines, Nasolabial Folds, and Crow’s Feet in a Double-Blind, Vehicle-Controlled Clinical Trial

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INTRODUCTIONFacial rhytides arise due to diminished production and increased breakdown of dermal matrix components, including collagen, glycosaminoglycans (GAGs), and elastin, as a result of natural aging and photodamage, coupled with…
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Dec 10
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A Substitute for Skin Grafts, Flaps, or Internal Tissue Expanders in Scalp Defects Following Tumor Ablative Surgery

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INTRODUCTION Scalp defects that cannot be primarily closed impose a significant challenge during tumor ablative and reconstructive surgery. Frequently, direct closure is not possible due to the limited elasticity of…
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Dec 10
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Long-Term Safety and Efficacy of Once-Daily Topical Brimonidine Tartrate Gel 0.5% for the Treatment of Moderate to Severe Facial Erythema of Rosacea: Results of a 1-Year Open-Label Study

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INTRODUCTIONRosacea is a common inflammatory skin disorder estimated to affect 16 million Americans.1 Although it is usually observed in patients with light skin phototype, rosacea has also been diagnosed in…
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Dec 10
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Prolonged Adverse Events Following Photodynamic Therapy: Regulatory Implications

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BACKGROUND Photodynamic therapy (PDT) has become an established option in the management of actinic keratoses (AKs) and other skin diseases. Cutaneous PDT has predominantly involved the use of methyl aminolevulinate…
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Dec 10
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Midface and Perioral Volume Restoration: A Conversation Between the US and Italy

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INTRODUCTIONFacial appearance is a defining hallmark of identity and self-confidence.1, 2 Changes in skin quality, such as the loss of elasticity and decreased dermal thickness, in addition to alterations in…
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Dec 10
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Successful Use of 1064 Nm Nd:YAG in Conjunction With 2790 Nm YSGG Ablative Laser for Traumatic Scarring

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INTRODUCTION Patients with traumatic scarring often seek both aesthetic and functional improvement and can be a challenge to treat; however, advances in laser and light technologies have helped to treat…
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Dec 10
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Combined Topical Delivery and Dermalinfusion of Decapeptide-12 Accelerates Resolution of Post-Inflammatory Hyperpigmentation in Skin of Color

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The combined use of topical delivery and dermalinfusion® of decapeptide-12 represents a novel, safe, and efficacious noninvasive approach to achieve accelerated resolution of postinflammatory hyperpigmentation (PIH), an especially difficult to…
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Dec 10
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Resident Rounds. Part I. Program Spotlight: Washington University School of Medicine

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Dermatology at Washington University The tradition of Dermatology at Washington University School of Medicine can be best traced back to the earliest history of the Siteman Cancer Center in the…
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