EpidemiologyThough MF is the most common subtype of CTCL, it is still a relatively uncommon malignancy. United States data is obtained from cancer registries that take part in the Surveillance,…

Lambrolizumab for Advanced Melanoma Merck has announced that the FDA has designated lambrolizumab (MK-3475) as a Breakthrough Therapy for the treatment of patients with advanced melanoma. Lambrolizumab is Merck’s investigational…

INTRODUCTIONHyaluronic acid (HA) is a glycosaminoglycan composed of alternating D-glucuronic acid and N-acetyl- D-glucosamine monosaccharide residue. These are cross-linked to form long unbranched chains, which form an anionic biopolymer. The…

INTRODUCTIONPhotodynamic therapy (PDT) has been a relatively late addition to the treatment modalities available to the dermatologist.5 This review will provide a survey of recent preclinical and clinical data that…

Within the world of medical dermatology, the treatment of psoriasis remains a central focus of investigation and innovation. While we have an array of topical, oral, and parenteral treatments already,…

I read with great interest the original article entitled “Postoperative Wound Care After Dermatologic Procedures: A Comparison of 2 Commonly Used Petrolatum-Based Ointments,” by Adisbeth Morales-Burgos MD, Michael P. Loosemore…

INTRODUCTION Psoriasis is a chronic, immune-mediated inflammatory skin disorder that affects 2-3% of Americans.1, 2 Plaque psoriasis is the most common form, accounting for 90% of psoriatic cases.2, 3 Classically,…

INTRODUCTIONPsoriasis is a chronic immune-mediated disorder commonly manifesting as silver-scaly plaques on an erythematous base, that has been reported at rates of up to 6.5% in certain areas of the…

INTRODUCTION Psoriasis is a common chronic inflammatory skin disease, with a strong genetic basis characterized by complex alterations in epidermal growth and differentiation. The disease is enormously variable in duration…

INTRODUCTIONPsoriasis patients may experience a significantly impaired health-related quality of life (HRQoL),1,2 causing negative psychosocial effects such as feelings of stress, stigmatization, embarrassment, and self-consciousness.3,4 Active disease is also associated…

INTRODUCTION A two-compound ointment containing 50 μg/g calcipotriene plus 0.5 mg/g betamethasone (as dipropionate) has good efficacy and is a safe treatment for psoriasis vulgaris of the body.1 However, in…

INTRODUCTIONPsoriasis treatment with traditional systemic or biologic therapies may be compromised by safety and tolerability concerns, administration (injection versus oral), and lack/loss of response.1-5 Efficacious, safe, well-tolerated, and easy-to-use treatment…