ONYCHOMYCOSES1320 nm Nd:YAG Laser for Improving the Appearance of Onychomycosis Sponsored by the University of California, Irvine, the purpose of this clinical study is to improve the appearance of onychomycosis…

This month's celebration editorial features Dr. Bill Levis, Senior Editor of the JDD. Dr. Levis was a Senior Investigator for the National Cancer Institute for 11 years specializing in skin…

This year is a monumental one for the Journal of Drugs in Dermatology (JDD) as it celebrates its tenth year anniversary. I remember receiving the JDD as a resident, first…

INTRODUCTIONTherapy of actinic keratosis (AK) using imiquimod 5% cream (Aldara, MEDA Pharmaceuticals, Somerset, NJ) was approved in the United States and European Union in 2005 and 2006, respectively. Despite the…

INTRODUCTION Hispanics represent the largest and fastest growing minority group in the United States. Over the past decade the Hispanic population has increased by 43% and now accounts for 16.3%…

INTRODUCTIONHuman cutaneous malignant melanoma is one of the most resistant tumors to treat, being responsible for 75% of skin cancer-related deaths.1Despite improvements in the management of this tumor, its treatment…

INTRODUCTIONDiscrete actinic keratoses (AKs) may be treated by cryosurgery with liquid nitrogen, curettage with electrodessication, topical creams (imiquimod, 5-fluorouracil, diclofenac), or surgery; however, targeted therapeutic modalities are not as effective…

INTRODUCTIONActinic keratosis (AK) is a chronic disease and part of a biologic continuum between photodamaged skin and invasive squamous cell carcinoma (SCC).1 Long-term management is required for AK because photodamage…

INTRODUCTIONTumor necrosis factor (TNF) inhibitors are a relatively new treatment used for a wide variety of inflammatory skin diseases. As their use increases, the prevalence of rare adverse events also…

INTRODUCTION Present in a wide variety of tissues and fluids, epidermal growth factor protein (EGF) acts on a subset of the tyrosine kinase receptor family.1 Epidermal growth factor serves primarily…

INTRODUCTION Scientific evidence supporting the optimal treatment for autoimmune mucocutaneous blistering diseases (AMBD) today has not been established.1 High dose systemic corticosteroids are often cited as first line therapy. Because…

INTRODUCTION Frank Macfarlane Burnet won the Nobel Prize for the clonal selection theory of immunity in 1960. 1 In 1961, Miller published evidence that these lymphocyte "clones" were educated in…