Oregano Extract Ointment for Wound Healing: A Randomized, Double-Blind, Petrolatum-Controlled Study Evaluating Efficacy

October 2011 | Volume 10 | Issue 10 | Original Article | 1168 | Copyright © October 2011


Jennifer Ragi MD,a Amy Pappert MD,a Babar Rao MD,a Daphna Havkin-Frenkel PhD,b Sandy Milgraum MDa

aDepartment of Dermatology, University Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Somerset, NJ bDepartment of Plant Pathology and Biology, Rutgers University, New Brunswick, NJ

table 3
domized, controlled trials using oregano water-soluble extract ointment in different concentrations for wound healing are needed. Oregano extract ointment has unique antibacterial, antifungal, anti-inflammatory, and antioxidant properties. In this randomized, petrolatum-controlled study, oregano ointment decreased bacterial contamination and acute infection on post-surgical excision wounds. Oregano extract was well tolerated without significant adverse reactions. Further large-scale, randomized, controlled trials using oregano water-soluble extract ointment for wound healing are needed.

DISCLOSURES

Dr. Daphna Havkin Frenkel is Vice President, and Director of Research and Development for Bakto Flavors, LLC.
Drs. Ragi, Pappert, Rao, and Milgraum have no relevant conflicts of interest.

REFERENCES

  1. Kirsner RS, Eaglstein WH. The Wound Healing Process. Dermatol Clin. 1993; 11(4): 629-640.
  2. Kirsner RS. Wound Healing. In: Bolognia JL, Jorizzo JL, Rapini RP, editors. Dermatology. Mosby; 2003:2207-2218.
  3. Jacobs, S, James, W. Bacitracin after clean surgical procedures may be risky. J Am Acad Dermatol 2004; 51(6):1036.
  4. Zappi EG, Brancaccio RR. Allergic contact dermatitis from mupirocin ointment. J Am Acad Dermatol. 1997; 36:266.
  5. Marks JG Jr, Belsito DV, Deleo VA, et al. North American Contact Dermatitis Group Patch-Test Results, 1996-1998. Arch Deramtol. 2000; 136:272-273.
Close Menu