Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream

March 2024 | Volume 23 | Issue 3 | 141 | Copyright © March 2024


Published online February 28, 2024

Hilary E. Baldwin MDa, Craig Arrowitz b, James Del Rosso DOc

aAcne Treatment and Research Center, Brooklyn, NY 
bBeiersdorf Inc., Florham, NJ 
cDermatology Research Center, Las Vegas, NV

The lasting effect of Improvement in skin hydration was evaluated at day 15 (5-day regression with no additional moisturization). The ceramide plus NMF cream 10-day moisturization plus 5-day regression yielded a 32.2% increase from baseline corneometer units (P<0.001), while the ceramide cream yielded a 22.8% increase from baseline corneometer units (P<0.05) (Figure 2). 

Ceramide Plus NMF Lotion vs Ceramide Cream
To address the misconception that creams are always more efficacious than lotions, we evaluated the clinical efficacy of improvement in skin hydration after 10 days of daily use of the ceramide plus NMF lotion compared to the ceramide cream, followed by corneometer assessment at day 15 following a 5-day