Individual Article: Over-the-Counter Moisturizers Significantly Improve Skin Hydration in Adults With Eczema/Atopy-Prone Skin

October 2023 | Volume 22 | Issue 10 | SF388641s16 | Copyright © October 2023


Published online September 30, 2023

Harrison Nguyen MD MBA MPHa, Thu Nguyen PhDb, Ana Mantilla DPMb, Christine Emesiani PharmDb, Matthew Meckfessel PhDb

aDepartment of Dermatology, University of Pennsylvania, Philadelphia, PA 
bGalderma Laboratories, L.P., Dallas, TX


RESULTS

A total of 30 healthy male and female patients participated in the study, with participant demographics shown in Table 1.

Effectiveness
Both products significantly improved skin hydration at week 4 vs baseline as demonstrated by corneometer measurements (Figure 1) with a mean difference from baseline of 10.8 for ESM and 6.0 for IRML (P less than or equal to 0.001 for both) at the arm site and 6.6 for ESM and 3.4 for IRML in the leg (P less than or equal to 0.001) for both. However, skin hydration was significantly higher in the ESM-treated areas compared to the IRML at week 4 (P<0.05).