reduction of abdominal or posterior flank adiposity. Subjects could opt for a second laser treatment at the same or different site at a 6-week follow-up.7 Based on photographic evidence from follow-up visits, all 5 blinded investigators correctly assigned the photos to their proper sequence based on overall treatment results over time and concurred with improved skin quality and reduced laxity. No adverse events were reported.7 Limitations of this study included lack of objective outcome measures and the small number of subjects; moreover, there was no historical or concurrent control group, making it impossible to discern whether the observed effects simply reflected normal recovery following SculpSure treatment.
An earlier study evaluating skin quality improvements using the same formulation following bipolar radiofrequency (RF) treatment for posterior buttock/thigh adiposity showed consistent results.3 In an 8-week, split-body study, 20 female subjects received RF treatment (Accent XL; Alma Lasers Inc., Buffalo Grove, IL) plus BTC on one buttock/thigh, while the other buttock/thigh received RF treatment only. At week 8, the buttock/thigh receiving the RF treatment plus BTC experienced significant improvements in skin tone, radiance, texture, firmness/tightness, and overall appearance compared with RF treatment alone. Although thigh circumference was significantly reduced from baseline on both sides at 8 weeks, the reduction was consistent on each side (≈1%).3
In a randomized, split-body study, Kavali and colleagues evaluated BodiFirm (Revision Skincare, Irving, TX) for skin quality improvement in female patients (N=40; mean age,
