Differentiation of NASHA and OBT Hyaluronic Acid Gels According to Strength, Flexibility, and Associated Clinical Significance

January 2024 | Volume 23 | Issue 1 | 1332 | Copyright © January 2024


Published online December 12, 2023

Ake Ohrlund MSc, Per Winlof BSc, Torun Bromee PhD, Inna Prygova MD

Galderma, Uppsala, Sweden

Kysse), 171 (R. Volyme), and 271 (R. Defyne) Pa, respectively (Figure 1 and Table 1).  

HA fillers produced with OBT technology demonstrated the highest xStrains (flexibility), comprising 1,442%, 908%, 930%, and 761% for R. Refyne, R. Kysse, R. Volyme, and R. Defyne, respectively. NASHA formulations showed xStrains of 7% (Restylane), 19% (R. Silk), and 17% (R. Lyft) (Figure 2 and Table 1).  

The combined characteristics of each HA filler in terms of strength/firmness (G') and flexibility (xStrain) are plotted in Figure 3.