Single-Center, Double-Blind, Randomized, Placebo-Controlled, Study of the Efficacy and Safety of a Cream Formulation for Improving Facial Wrinkles and Skin Quality

June 2018 | Volume 17 | Issue 6 | Original Article | 664 | Copyright © June 2018

Neil Sadick MD,a,b Krista Bohnert BS,b Monica Serra,b and Neal Kitchen PhDc

aWeill Cornell Medical College, Cornell University, New York, NY bSadick Dermatology and Research, New York, NY cHydroPeptide LLC, Issaquah, WA

Figure2Figure3strated statistically significant improvements in GAIS (P=0.03 and P=0.04, respectively; Figure 4, 5). Collectively, investigator assessments for the face showed moderate improvement in 64% of subjects, mild improvement in 27% of subjects and no change in 21% of subjects.Subject AssessmentsAll of the subjects included in the study used the tested materials as instructed and reported the product to be easy and convenient to add a daily skincare routine. There was a 1-point increase in subject treatment satisfaction scale rating scores