Safety and Efficacy of a Non-Invasive 1060 nm Diode Laser for Fat Reduction of the Abdomen

January 2018 | Volume 17 | Issue 1 | Original Article | 106 | Copyright © January 2018

Lawrence S. Bass MD FACSa and Sean T. Doherty MD FACSb

aDepartment of Plastic Surgery, Manhattan Eye, Ear & Throat Hospital, Hofstra Northwell School of Medicine, New York, NY bDivision of Plastic Surgery, Department of Surgery, Emerson Hospital, Concord, MA


  1. American Society for Aesthetic Plastic Surgery. Statistics. Cosmetic Surgery National Data Bank. 2013. Accessed January 28, 2015.
  2. Gadsden E., Aguilar M.T., Smoller B.R., Jewell M.L. Evaluation of a Novel High-Intensity Focused Ultrasound Device for Ablating Subcutaneous Adipose Tissue for Noninvasive Body Contouring : Safety Studies in Human Volunteers. Aesthetic Surgery Journal. 2011; 31(4):401-410.
  3. Fatemi A. High-intensity focused ultrasound effectively reduces adipose tissue. Semin Cutan Med Surg. 2009 Dec;28(4):257-62.
  4. Franco W, Kothare A, Ronan SJ, Grekin RC, McCalmont TH. Hyperthermic injury to adipocyte cells by selective heating of subcutaneous fat with a novel radiofrequency device: feasibility studies. Lasers Surg Med. 2010;42(5):361-370.
  5. Decorato J, Sierra R, Chen B. Clinical and histological evaluations of a novel 1060nm laser device for non-invasive fat reduction. 34th Annual American Society for Laser Medicine and Surgery Meeting; April 2014; Phoenix, AZ. Abstract No.
  6. Chen B, Sierra R, Katz B, Doherty S, Bass L. Objective evaluation of fat reduction treatment with a non-invasive 1060 nm diode laser. 35th Annual American Society for Laser Medicine and Surgery Meeting; April 2015; Kissimmee, Fl. Abstract No.
  7. Krueger N, Mai SV, Luebberding S, Sadick NS. Cryolipolysis for noninvasive body contouring: clinical efficacy and patient satisfaction. Clinical, Cosmetic and Investigational Dermatology. 2014:7 201–205.
  8. Avram MM, Harry RS. Cryolipolysis for subcutaneous fat layer reduction. Lasers Surg Med. 2009 Dec;41(10):703-708.
  9. Manstein D, Laubach H, Watanabe K, Farinelli W, Zurakowske D, Anderson RR. Selective cryolysis: A novel method of non-invasive fat removal. Lasers Surg Med. 2008;40:595– 604.
  10. Zelickson B, Egbert BM, Preciado J, Allison J, Springer K, Rhoades RW, Manstein D. Cryolipolysis for Noninvasive Fat Cell Destruction: Initial Results from a Pig Model. Dermatol Surg. 2009;35:1–9.
  11. Klein KB, Zelickson B, Riopelle JG, Okamoto E, Bachelor EP, Harry RS, Preciado JA. Non-invasive cryolipolysis for subcutaneous fat reduction does not affect serum lipid levels or liver function tests. Lasers Surg Med. 2009 Dec;41(10):785-90.
  12. Ingargiola MJ1, Motakef S, Chung MT, Vasconez HC, Sasaki GH. Cryolipolysis for fat reduction and body contouring: safety and efficacy of current treatment paradigms. Plast Reconstr Surg. 2015 Jun;135(6):1581-90.
  13. He X, Bischof JC. Quantification of temperature and injury response in thermal therapy and cryosurgery. Crit Rev Biomed Eng. 2003;31(5-6):355-422.
  14. Gaylor, D. C. Physical mechanism of celluar injury in electrical trauma. Massachusetts Institute of Technology. Ph. D. Dissertation. (1989).
  15. Moussa N, Tell E, Cravalho E. Time progression of hemolysis or erythrocyte populations exposed to supraphysiologic temperatures. J Biomech Eng 1979, 101:213-217.
  16. Goldman A, Gotkin RH. Laser-assisted liposuction. Clin Plast Surg. 2009 Apr;36(2):241-53, vii; discussion 255-60.
  17. Woodhall KE, Saluja R, Khoury J, Goldman MP.A comparison of three separate clinical studies evaluating the safety and efficacy of laser-assisted lipolysis using 1,064, 1,320 nm, and a combined 1,064/1,320 nm multiplex device. Lasers Surg Med. 2009 Dec;41(10):774-8.
  18. Jewell ML, Baxter RA, Cox SE, et al. Randomized sham-controlled trial to evaluate the safety and effectiveness of a high-intensity focused ultrasound ultrasound device for noninvasive body sculpting. Plast Reconstr Surg. 2011;128:253-262.
  19. Saedi N, Kaminer M. New waves for fat reduction: high-intensity focused ultrasound. Semin Cutan Med Surg. 2013 Mar;32(1):26-30.
  20. Ascher B. Safety and efficacy of UltraShape Contour I treatments to improve the appearance of body contours: multiple treatments in shorter intervals. Aesthet Surg J. 2010 Mar;30(2):217-224.
  21. Boisnic S, Divaris M, Nelson AA, Gharavi NM, Lask GP. A clinical and biological evaluation of a novel, noninvasive radiofrequency device for the long-term reduction of adipose tissue. Lasers Surg Med. 2014 Feb;46(2):94-103.
  22. Zelickson BD, Burns AJ, Kilmer SL. Cryolipolysis for safe and effective inner thigh fat reduction. Lasers Surg Med. 2015 Jan 13.


Lawrence S. Bass MD