Mitozantrone-Induced Onycholysis Associated with Subungual Abscesses, Paronychia, and Pyogenic Granuloma

July 2005 | Volume 4 | Issue 4 | Case Reports | 490 | Copyright © July 2005

Anatoli Freiman MD, Nathaniel Bouganim MD, Elizabeth A. O’Brien MD FRCPC

Abstract
Chemotherapeutic agents may induce a wide variety of adverse mucocutaneous effects, including nail changes. We present a case of atypical onycholysis, associated with subungual abscess formation, paronychia and pyogenic granuloma resulting from the use of mitozantrone, an antineoplastic cytotoxic agent, in the treatment of metastatic prostate cancer.