deep structures, though literature is scarce when it comes to published studies on the aspect and repercussions of this product in hyperdiluted conditions, which is the currently recommended technique by international consensus for treating the neck skin, decolletage, and body.4,5
OBJECTIVE
To assess possible interferences in thyroid ultrasonographic
evaluation after the treatment of the cervical region with
hyperdiluted calcium hydroxyapatite in the subdermal plane, as
well as to evaluate related findings to the product application in
this dilution in the above-mentioned anatomic region.
MATERIALS AND METHODS
This was a prospective, blinded, and controlled study conducted at Instituto Boggio, São Paulo, Brazil. All ethical policies recommended by the journal were strictly followed, exactly as stated in the guidelines for authors. The study was duly appreciated by the ethics committee of Hospital Moriah (Sao Paulo - Brazil) under number CAAE: 58517922.3.0000.8054 and favorable opinion under number: 5.488.636. The subjects signed the written informed consent form.
Patients complaining about sagging in the cervical region, without contraindications, and who did not have previous treatment with biostimulators, were selected and divided into two groups.
The first group was composed of 10 women who underwent conventional treatment of the cervical region with 1.5 mL of calcium hydroxyapatite in a 1:4 dilution by linear retroinfusion technique and using a micro cannula of 22 Gauge. Five vectorized figures composed of 7 points were marked, one in the submental and two in each side of the neck, according to the outlines in the image (Figure 2) standardized in a previously published study.6
The second group (control) included 5 women of the same age range, with no previous injectable treatment in the cervical region. All injectable procedures were conducted on the same day by the authors. Dilution of hydroxyapatite was done with 1.5 ml of product with the addition of 1.5 ml of lidocaine 2% and 4.5 ml of saline solution.
Patients were evaluated by two radiologists with experience in dermatologic ultrasound examinations. Radiologists were blinded regarding treated or untreated subjects (groups 1 and 2) with emphasis on both: the findings concerning the product, and its relationship with the thyroid assessment.
Patients complaining about sagging in the cervical region, without contraindications, and who did not have previous treatment with biostimulators, were selected and divided into two groups.
The first group was composed of 10 women who underwent conventional treatment of the cervical region with 1.5 mL of calcium hydroxyapatite in a 1:4 dilution by linear retroinfusion technique and using a micro cannula of 22 Gauge. Five vectorized figures composed of 7 points were marked, one in the submental and two in each side of the neck, according to the outlines in the image (Figure 2) standardized in a previously published study.6
The second group (control) included 5 women of the same age range, with no previous injectable treatment in the cervical region. All injectable procedures were conducted on the same day by the authors. Dilution of hydroxyapatite was done with 1.5 ml of product with the addition of 1.5 ml of lidocaine 2% and 4.5 ml of saline solution.
Patients were evaluated by two radiologists with experience in dermatologic ultrasound examinations. Radiologists were blinded regarding treated or untreated subjects (groups 1 and 2) with emphasis on both: the findings concerning the product, and its relationship with the thyroid assessment.
