An Overview of Biologics for Psoriasis

November 2021 | Volume 20 | Issue 11 | Features | 1246 | Copyright © November 2021


Published online October 18, 2021

Rachna Dave MD and Amena Alkeswani MD

University of Tennessee Health Science Center, Memphis, TN

DISCUSSION

The authors have disclosed no conflicts.

REFERENCES

1. Menter A, Strober BE, Kaplan DH, et al. Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with biologics. J Am Acad Dermatol. 2019;80(4):1029-1072.
2. Kaushik SB, Lebwohl MG. Psoriasis: Which therapy for which patient: Psoriasis comorbidities and preferred systemic agents. J Am Acad Dermatol. 2019;80(1):27-40.
3. Kaushik SB, Lebwohl MG. Psoriasis: Which therapy for which patient: Focus on special populations and chronic infections. J Am Acad Dermatol. 2019;80(1):43-53.
4. Papp KA, Lebwohl MG. Onset of action of biologics in patients with moderate- to-severe psoriasis. J Drugs Dermatol. 2017;17(3):247-250.
5. Nehring P, Przybylkowski A. Is psoriasis treatment a risk factor for inflammatory bowel disease? Pharmaceut Med. 2020;34(4):257-262.
6. Lebwohl M, Blauvelt A, Paul C, et al. Certolizumab pegol for the treatment of chronic plaque psoriasis: Results through 48 weeks of a phase 3, multicenter, randomized, double-blind, etanercept- and placebo-controlled study (CIMPACT). J Am Acad Dermatol. 2018;79(2):266-276 e265.
7. Mariette X, Forger F, Abraham B, et al. Lack of placental transfer of certolizumab pegol during pregnancy: results from CRIB, a prospective, postmarketing, pharmacokinetic study. Ann Rheum Dis. 2018;77(2):228-233.
8. Tremfya. Package Insert. Available from: https://www.accessdata.fda.gov/ drugsatfda_docs/label/2020/761061s007lbl.pdf. Cited on: 10/30/2020.
9. Warren RB, Gooderham M, Burge R, et al. Comparison of cumulative clinical benefits of biologics for the treatment of psoriasis over 16 weeks: Results from a network meta-analysis. J Am Acad Dermatol. 2020;82(5):1138-1149.
10. Reich K, Armstrong AW, Foley P, et al. Efficacy and safety of guselkumab, an anti-interleukin-23 monoclonal antibody, compared with adalimumab for the treatment of patients with moderate to severe psoriasis with randomized withdrawal and retreatment: Results from the phase III, double-blind, placebo- and active comparator-controlled VOYAGE 2 trial. J Am Acad Dermatol. 2017;76(3):418-431.
11. Blauvelt A, Papp KA, Griffiths CE, et al. Efficacy and safety of guselkumab, an anti-interleukin-23 monoclonal antibody, compared with adalimumab for the continuous treatment of patients with moderate to severe psoriasis: Results from the phase III, double-blinded, placebo- and active comparatorcontrolled VOYAGE 1 trial. J Am Acad Dermatol. 2017;76(3):405-417.
12. Skyrizi. Package Insert. Available from: https://www.accessdata.fda.gov/ drugsatfda_docs/label/2019/761105s000lbl.pdf. Cited on: 10/30/2020.
13. Papp KA, Blauvelt A, Bukhalo M, et al. Risankizumab versus Ustekinumab for Moderate-to-Severe Plaque Psoriasis. N Engl J Med. 2017;376(16):1551- 1560.
14. Cosentyx. Package Insert. Available from: https://www.accessdata.fda.gov/ drugsatfda_docs/label/2020/125504s035lbl.pdf Cited on 10/30/2020.
15. Reich K, Leonardi C, Langley RG, et al. Inflammatory bowel disease among patients with psoriasis treated with ixekizumab: A presentation of adjudicated data from an integrated database of 7 randomized controlled and uncontrolled trials. J Am Acad Dermatol. 2017;76(3):441-448 e442.
16. Taltz. Package Insert. Available from: https://www.accessdata.fda.gov/drugsatfda_ docs/label/2019/125521s016lbl.pdf Cited on 10/30/2020.
17. Siliq. Package Insert. Available from: https://www.accessdata.fda.gov/drugsatfda_ docs/label/2017/761032lbl.pdf. Cited on: 10/30/2020.

AUTHOR CORRESPONDENCE

Amena Alkeswani MD aalkeswa@uthsc.edu