A Randomized Study on PLLA Using Higher Dilution Volume and Immediate Use Following Reconstitution

July 2021 | Volume 20 | Issue 7 | Original Article | 760 | Copyright © July 2021


Published online June 23, 2021

Melanie Palm MD MBA,a Susan Weinkle MD,b Younghoon Cho MD,c Brenda LaTowsky MD,d Heidi Prather MDe

aArt of Skin MD, Solana Beach, CA
bSusan H Weinkle MD, Bradenton, FL
cIntegrated Aesthetics, Spring, TX
dInvestigate MD, Scottsdale, AZ
eWestlake Dermatology Clinical Research Center, Austin, TX



baseline for both groups overlapped for both sides of the face, confirming a comparable treatment effect. Responder rates based on WAS were slightly higher for the reference group than the treatment group at earlier time points in the study, however this difference decreased over time and values were similar between the groups at week 48 (Figure 1). The mean change from baseline in WAS score at week 48 for FST I–III, FST IV, and FST V–VI subjects within the treatment group was similar for both sides of the face. Representative subject photographs are presented in Figures 2–3.