Current Issue
December 2025 | Volume 24 | Issue 12
Editorials
Original Articles
Impact of Low-Dose Oral Minocycline (DFD-29) on Skin, Gastrointestinal, and Vaginal Microflora in Healthy Adults
Background: DFD-29 (minocycline hydrochloride extended-release capsules, 40 mg) has shown significant therapeutic benefit vs placebo and doxycycline in treating moderate-to-severe rosacea. However, th...
Read MoreClinical Evaluation of Thiamidol-Containing Formulations for the Visual Management of Facial Hyperpigmentation
Background: Cutaneous hyperpigmentation, which includes melasma, post-inflammatory hyperpigmentation, and solar lentigines, significantly impacts patients' quality of life. The overproduction of melan...
Read MoreSkin Improvements in Acne Vulgaris Patients Using Gel-Matrix Moisturizer as a Complement to Topical Treatments
Background: A novel gel-matrix moisturizer was designed to 1) deliver immediate, long-lasting hydration benefits in a lightweight, non-greasy, noncomedogenic formula that is suitable for use on dry, o...
Read MoreGLP-1 Receptor Agonists in Hidradenitis Suppurativa: A Novel Therapeutic Approach for Hidradenitis Suppurativa and Its Comorbidities
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder associated with many comorbidities, including obesity, diabetes, cardiovascular risk factors, mental health issues, an...
Read MoreEvaluating the Risk of Atherosclerotic Cardiovascular Disease in Inflammatory Skin Disease: Insights From a TriNetX Cohort Study
Objective: Recognizing the risk of atherosclerotic cardiovascular disease (ASCVD) in patients is crucial in clinical practice. Recent studies suggest an association between inflammatory skin diseases ...
Read MoreReport From the 2024 International Dermatology Outcome Measures (IDEOM) Annual Meeting
Background: International Dermatology Outcome Measures (IDEOM) is a nonprofit organization committed to advancing the development and accessibility of evidence-based, consensus-driven outcome measures...
Read MoreClindamycin Phosphate 1.2%/Adapalene 0.15%/ Benzoyl Peroxide 3.1% Gel for Moderate-to-Severe Acne: A Pooled Analysis by Age
Background: Acne pathophysiology and presentation may differ between pediatric/adolescent/young adult (9-24 years) and adult (≥25 years) patients. Fixed-dose clindamycin phosphate 1.2%/adapalene 0....
Read MoreIsotretinoin Does Not Increase the Risk of Inflammatory Bowel Disease: A TriNetX Retrospective Cohort Analysis
Background: Background: The increasing use of long-term, low-dose isotretinoin for acne has raised concerns about a potential association with inflammatory bowel disease (IBD), including Crohn's disea...
Read MoreDisparities in Hidradentitis Suppurativa Clinical Trials: An Updated Review of ClinicalTrials.gov from 2020 to 2024
Background: There is a notable lack of diversity in dermatologic studies, even concerning conditions that are known to have a higher prevalence in the skin of color (SOC) population, such as hidradeni...
Read MoreAn Open-Label, Single-Center Proof of Concept Study Evaluating the Efficacy and Safety of Tirzepatide for Moderate to Severe Hidradenitis Suppurativa
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disease associated with obesity and metabolic dysregulation. Current therapies yield variable benefits and do not target metabolic d...
Read MoreMore Than Skin Clearance: Connecting Brodalumab's Mechanism of Action to Patient Outcomes in Psoriasis
Psoriasis has profound negative impacts on quality of life (QOL), including stigmatization, discrimination, occupational challenges, and mental health concerns, which are correlated with disease sever...
Read MoreThe Current Landscape of Treatment of Warts
Warts have bothered people since the early Greek and Roman empires.5 For centuries, people have studied causes of and treatments for these irritating tumors. In recent history, treatments have stagnat...
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Features
FDA Boxed Warnings: Should Package Inserts Include Levels of Evidence?
Many medications commonly used in dermatology come with package inserts that contain boxed warnings that are frequently not evidence-based. Boxed warnings are the most serious warnings that the US Foo...
Read MoreThe Overlooked Burden: Psychodermatologic Needs of Hispanic and Latinx Communities in the United States
National Institutes of Health Funding for Vitiligo Research: Trends from 1985 to 2024
Background: The National Institutes of Health (NIH) funds a multitude of dermatology research. This study examines NIH funding for vitiligo studies and highlights key trends. Methods: The NIH Researc...
Read MoreScar Wars: A Review of Topical Scar Therapies
Maximizing a Focused Vitiligo Patient Visit: A Practical Approach
Case Reports
Resolution of Lichen Simplex Chronicus With Nemolizumab: A Case Report
Introduction: Lichen simplex chronicus is a debilitating condition characterized by lichenified skin secondary to intractable itch. Lichen simplex chronicus is challenging to treat, with current treat...
Read MorePyoderma Gangrenosum Following Total Colectomy for Ulcerative Colitis
Departments
FULL SUPPLEMENT: Nordic European Cutaneous Oncodermatology Management (Necom) 7: Real-World Cases Applying Recommendations for the Prevention and Treatment of Skin Reactions Related to Cancer Therapies Using Skin-Protective Measures
The current risk of getting cancer before age 80 in Nordic countries is estimated at 42.7% in males and 36.2% in females. Based on the collaborative Nordic cancer registry (NORDCAN), breast, lung, and...
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Supplements
INDIVIDUAL ARTICLE: NECOM 7: Real-World Cases on Preventive and Treatment Using Skin Care for Cancer Treatment-Related Skin Reactions
As cancer prevalence continues to increase in Nordic countries, the amount of dermatological adverse events, termed cutaneous adverse events (cAEs), will also increase. The Nordic European Cutaneous O...
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