Found 27 articles for: "Hyperpigmentation"
A Novel Retinoid and Salicylic Acid Topical Treatment for Moderate-Severe Acne
June 2026 | Volume 25 | Issue 6 | Original Article | 558 | Copyright © June 2026
Background: Advances in biotechnology have enabled highly effective, site-specific topical therapies for skin disease. Particle-based delivery systems can be engineered with tail...
Read MoreIron Oxides in Tinted Sunscreen for Hyperpigmentation: A Product Analysis and Literature Review
May 2026 | Volume 25 | Issue 5 | Original Article | 440 | Copyright © May 2026
Background: Hyperpigmentation disproportionately affects skin of color, often exacerbated by visible light (VL) exposure. Photoprotection in these populations remains underused d...
Read MoreAn Investigator-Developed Regimen for Treatment and Prevention of Post-Inflammatory Hyperpigmentation in Skin of Color
April 2026 | Volume 25 | Issue 4 | Original Article | 330 | Copyright © April 2026
Background: There is an unmet demand for a post-inflammatory hyperpigmentation (PIH) treatment and prevention that is not only effective and accessible, but also safe to use in d...
Read MoreHydroquinone and Emerging Depigmenting Agents: Clinical Guidelines, Regulatory History, and Global Safety Considerations
April 2026 | Volume 25 | Issue 4 | Original Article | 363 | Copyright © April 2026
Hydroquinone has long served as the gold standard for hyperpigmentation treatment, but safety concerns, regulatory changes, and growing interest in non-hydroquinone therapies have prompted reeval...
Read MoreRapid Clearance of Lichen Planus With Topical Tapinarof
April 2026 | Volume 25 | Issue 4 | Case Reports | 381 | Copyright © April 2026
Background: Lichen planus (LP) is an auto-inflammatory idiopathic condition affecting skin, mucous membranes, hair follicles, and nails that presents as pruritic, violaceous papu...
Read MoreEfficacy and Safety of Cysteamine-Isobionic Amide Complex in the Treatment of Periorbital Hyperpigmentation
February 2026 | Volume 25 | Issue 2 | Original Article | 140 | Copyright © February 2026
Periorbital hyperpigmentation is a common yet challenging cosmetic concern due to the thin, vascular, and pigment-prone nature of periocular skin, as well as its multifactorial etiology. Discolor...
Read MoreA Novel Topical Agent for the Management of Hyperpigmentation, Including Melasma and Age Spots
January 2026 | Volume 25 | Issue 1 | Original Article | 75 | Copyright © January 2026
Background/Objectives: Melasma and age spots are among the most persistent and difficult-to-treat forms of hyperpigmentation. While traditional therapies offer some clinical effi...
Read MoreEvaluation of an Advanced, Multimodal Skin Tone Correcting Serum in Participants With Mild-to-Severe Dyschromia and Hyperpigmentation
January 2026 | Volume 25 | Issue 1 | Original Article | 36 | Copyright © January 2026
Background: A new multimodal skin tone correcting serum formulated with b.r.y.t.e.r. (brown, red, and yellow tones with enhanced resurfacing) technology (EV-I) targets brown, red...
Read MoreClinical Evaluation of a Thiamidol-Based Regimen With SPF Compared With SPF Alone for Facial Hyperpigmentation
January 2026 | Volume 25 | Issue 1 | Original Article | 48 | Copyright © January 2026
Read MoreA Randomized, Controlled, Split-Face, Double-Blind Study Comparing Topical Malassezin to Hydroquinone 4% for Melasma
January 2026 | Volume 25 | Issue 1 | Original Article | 25 | Copyright © January 2026
Background: Previous studies have documented the capacity of malassezin to brighten the skin. It represents a novel agent for the treatment of hyperpigmentation.Photodistributed Hyperpigmentation Associated With COVID-19 Vaccination
January 2026 | Volume 25 | Issue 1 | Case Reports | 93 | Copyright © January 2026
Background: Although drugs are a common cause of hyperpigmentation, the pathogenesis is unclear and varies based on the offending agent. Classic medications associated with hyper...
Read MoreClinical Evaluation of Thiamidol-Containing Formulations for the Visual Management of Facial Hyperpigmentation
December 2025 | Volume 24 | Issue 12 | Original Article | 1195 | Copyright © December 2025
Read MoreThe Impact of Hyperpigmentation on the Lives of Patients
July 2025 | Volume 24 | Issue 7 | Original Article | 668 | Copyright © July 2025
Hyperpigmentation is a prevalent condition that disproportionately impacts individuals with skin of color, diminishing their quality of life and psychosocial well-being. There is a need to better...
Read MoreThe Impact of Increasing Skin of Color Representation in the Pre-Clerkship Dermatology Curriculum
July 2025 | Volume 24 | Issue 7 | Editorials | e50 | Copyright © July 2025
Thiamidol: A Breakthrough Innovation in the Treatment of Hyperpigmentation
June 2025 | Volume 24 | Issue 6 | Original Article | 608 | Copyright © June 2025
Cutaneous hyperpigmentation, including melasma, solar lentigines, and post-inflammatory hyperpigmentation (PIH), results in a significant impact on patients’ quality of life. Unfortunately,...
Read MoreTreatment of Acne-Induced Macular Hyperpigmentation in Fitzpatrick Skin Types V - VI: A Scoping Review
June 2025 | Volume 24 | Issue 6 | Original Article | 579 | Copyright © June 2025
Acne-induced macular hyperpigmentation (AMH) is a common issue among patients with highly melanated skin, particularly those with Fitzpatrick Skin Types (FST) V - VI, which includes nonwhite pati...
Read MoreIsobutylamido Thiazolyl Resorcinol (Thiamidol) for Combatting Hyperpigmentation: A Systematic Review of Clinical Studies
November 2024 | Volume 23 | Issue 11 | Original Article | 986 | Copyright © November 2024
Background: Tyrosinase is the rate-limiting enzyme of melanogenesis and thus an ideal inhibitory target for treating hyperpigmentation. There are many commercially available tyro...
Read MoreA Single-Center, Open-Label, Prospective Study of a 589/1319 nm Dual Wavelength Laser for the Treatment of Facial Hyperpigmentation
November 2024 | Volume 23 | Issue 11 | Original Article | 943 | Copyright © November 2024
Background: Facial hyperpigmentation, characterized by the excessive production of melanin in the skin, is a prevalent dermatological concern affecting individuals of various eth...
Read MoreExamining Racial Diversity in Hyperpigmentation and Post-Inflammatory Hyperpigmentation Clinical Trials in the United States
July 2024 | Volume 23 | Issue 7 | Editorials | e158 | Copyright © July 2024
Postinflammatory Hyperpigmentation Following Mohs Micrographic Surgery: An Observational Study
May 2024 | Volume 23 | Issue 5 | Original Article | 316 | Copyright © May 2024
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