Found 337 articles for: "eczema"
Doxycycline-Induced Solar Urticaria: A Report of Two Cases
November 2015 | Volume 14 | Issue 11 | Case Reports | 1358 | Copyright © November 2015
We report two cases of doxycycline-induced solar urticaria that developed shortly after initiation of therapy with persistence despite discontinuation. Consequently, dermatologists should be aware of ...
Read MoreIdentifying Signs of Tinea Pedis: A Key to Understanding Clinical Variables
October 2015 | Volume 14 | Issue 10 | Supplement Individual Articles | 42 | Copyright © October 2015
Tinea pedis is a frequently encountered dermatophytosis affecting the superficial skin of the feet, primarily of adults. The prevalence of tinea pedis has increased over the last several decades due t...
Read MoreOnychomycosis to Fungal Superinfection: Prevention Strategies and Considerations
October 2015 | Volume 14 | Issue 10 | Supplement Individual Articles | 32 | Copyright © October 2015
Onychomycosis is the most common fungal skin infection, and it is frequently seen in the setting of other concomitant fungal infections, the most common being tinea pedis. Infected nails become a rese...
Read MoreClinical Trial Review
October 2015 | Volume 14 | Issue 10 | Features | 1173 | Copyright © October 2015
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select ...
Read MoreCrisaborole Topical Ointment, 2% in Adults With Atopic Dermatitis: A Phase 2a, Vehicle-Controlled, Proof-of-Concept Study
October 2015 | Volume 14 | Issue 10 | Original Article | 1108 | Copyright © October 2015
BACKGROUND: A novel approach for treating atopic dermatitis (AD) is the inhibition of phosphodiesterase 4 (PDE4), an enzyme involved in the proinflammatory cascade. Crisaborole topical ointment, 2% is...
Read MoreClinical Trial Report
June 2015 | Volume 14 | Issue 6 | Features | 643 | Copyright © June 2015
Clinical Trial Review is a JDD department designed to provide physicians with information on drugs and devices undergoing clinical testing. It is our goal to inform the reader of the status of select ...
Read MoreFive-Year Trend in the Number of Dermatologic Clinical Drug Trials Registered on ClinicalTrials.gov
May 2015 | Volume 14 | Issue 5 | Original Article | 497 | Copyright © May 2015
BACKGROUND: There is a reported global decrease in the number of clinical trials conducted in recent years. We aimed to determine if this declining trend can be extrapolated to dermatologic clinical t...
Read MoreSteroid-Free Over-the-Counter Eczema Skin Care Formulations Reduce Risk of Flare, Prolong Time to Flare, and Reduce Eczema Symptoms in Pediatric Subjects With Atopic Dermatitis
May 2015 | Volume 14 | Issue 5 | Original Article | 478 | Copyright © May 2015
INTRODUCTION: Atopic dermatitis (AD) is a chronic skin condition associated with decreased barrier function resulting in periodic flare-ups of erythematous and pruritic lesions. Guidelines recommend d...
Read MorePolypodium Leucotomos Extract: A Status Report on Clinical Efficacy and Safety
March 2015 | Volume 14 | Issue 3 | Original Article | 254 | Copyright © March 2015
Various extracts of polypodium leucotomos (PLE) applied topically or taken orally have been shown to have several beneficial antioxidant, photoprotectant, antimutagenic, and immunoregulatory effects. ...
Read MoreLeflunomide: An Immune Modulating Drug That May Have a Role in Controlling Secondary Infections With Review of Its Mechanisms of Action
March 2015 | Volume 14 | Issue 3 | Original Article | 230 | Copyright © March 2015
BACKGROUND: Leflunomide (LEF) is an immune modulator used most commonly for rheumatoid arthritis (RA). The mechanisms of action of LEF also include anti-microbial effects, particularly anti-viral effe...
Read MoreCost-Effectiveness Study of Pediatric Atopic Dermatitis in Asia: Atopiclair vs. Regular Emollient (AD-ATOP)
February 2015 | Volume 14 | Issue 2 | Original Article | 169 | Copyright © February 2015
BACKGROUND: Atopic dermatitis (AD) is a highly prevalent, chronic relapsing condition in childhood with significant financial burden and impact on the quality of life of patients and caregivers. Proac...
Read MoreThe Skin Microbiome: Is There a Role in the Pathogenesis of Atopic Dermatitis and Psoriasis?
February 2015 | Volume 14 | Issue 2 | Original Article | 127 | Copyright © February 2015
Skin microbiome studies have elucidated clinically pertinent information regarding its potential role in the pathogenesis of certain inflammatory skin disorders. Two of the most commonly diagnosed chr...
Read MoreA Randomized Controlled Clinical Study to Evaluate the Effectiveness of an Active Moisturizing Lotion With Colloidal Oatmeal Skin Protectant Versus Its Vehicle for the Relief of Xerosis
October 2014 | Volume 13 | Issue 10 | Original Article | 1265 | Copyright © October 2014
Read MoreTransitioning From Brand to Generic With Topical Products and the Importance of Maintaining the Formulation and Therapeutic Profiles of the Original Product: Focus on Clocortolone Pivalate 0.1% Cream
July 2014 | Volume 13 | Issue 7 | Supplement Individual Articles | 77 | Copyright © July 2014
Topical corticosteroids (TCSs) are a major part of the foundation of treatment for a wide variety of eczematous and inflammatory skin disorders in both adults and children. Mid-potency TCSs represent ...
Read MoreNews, Views, and Reviews. Less May Be More for MRSA: The Latest on Antibiotics, the Utility of Packing an Abscess, and Decolonization Strategies
January 2014 | Volume 13 | Issue 1 | Features | 89 | Copyright © January 2014
The management of skin infections has evolved over time and new evidence suggests that less acute intervention may be as good or better. For acute treatment, evidence from the emergency medicine li...
Read MoreThe Phototoxic and Photoallergy Potential of Clindamycin Phosphate 1.2%/ Tretinoin 0.025% Gel for Facial Acne: Results of Two Single-Center, Evaluator-Blinded, Randomized, Vehicle-Controlled Phase 1 Studies in Healthy Volunteers
January 2014 | Volume 13 | Issue 1 | Original Article | 16 | Copyright © January 2014
BACKGROUND: A fixed-dose combination of clindamycin phosphate 1.2% and tretinoin 0.025% gel (VELTIN® (clindamycin phosphate and tretinoin) 1.2%/0.025% Gel [VELTIN]) (clindamycin/tretinoin gel) is cur...
Read MoreIdentifying Patients at Risk for Recurrent or Advanced BCC
November 2013 | Volume 12 | Issue 11 | Original Article | 1244 | Copyright © November 2013
Basal cell carcinoma (BCC) is a common skin cancer and its incidence is on the rise worldwide. Clinical presentation and histologic examination are used for diagnosis and to stratify BCCs as either l...
Read MoreEfficacy of Combination of Glycolic Acid Peeling With Topical Regimen in Treatment of Melasma
October 2013 | Volume 12 | Issue 10 | Original Article | 1149 | Copyright © October 2013
BACKGROUND: Various treatment modalities are available for management of melasma, ranging from topical and oral to chemical peeling, but none is promising alone. Very few studies are available regardi...
Read MorePimecrolimus Cream and Tacrolimus Ointment in the Treatment of Atopic Dermatitis: A Pilot Study on Patient Preference
October 2013 | Volume 12 | Issue 10 | Original Article | 1145 | Copyright © October 2013
Background: Pimecrolimus cream 1% is approved for mild to moderate atopic dermatitis in children older than two years of age and adults. Tacrolimus ointment 0.03% is approved for moderate to severe at...
Read MoreNutritional Clinical Studies in Dermatology
October 2013 | Volume 12 | Issue 10 | Original Article | 1104 | Copyright © October 2013
BACKGROUND & AIMS: Nutrition has long been associated with skin health, beauty, integrity and aging through multiple pathways and cofactors implicated in skin biology. The onset and clinical course of...
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