Found 77 articles for: "Leon H. Kircik"
A Double-Blind, Placebo-Controlled Pilot Study to Estimate the Efficacy and Tolerability of a Nonsteroidal Cream for the Treatment of Cradle Cap (Seborrheic Dermatitis)
April 2013 | Volume 12 | Issue 4 | Original Article | 448 | Copyright © April 2013
This study was a multicenter, double-blind, placebo-controlled, parallel-group pilot study of efficacy and tolerability of a nonsteroidal cream (Promiseb® Topical Cream; Promius Pharma, LLC, Brid...
Read MoreThe Only Topical Retinoid Without a Generic Alternative: Tazarotene
March 2013 | Volume 12 | Issue 3 | Supplement Individual Articles | 52 | Copyright © March 2013
A Randomized, Double-Blind Phase 4 Study of the Efficacy and Safety of Ethanol-Free Clobetasol Propionate Foam, 0.05%, vs Vehicle Foam in the Treatment of Chronic Hand Dermatitis
March 2013 | Volume 12 | Issue 3 | Original Article | 328 | Copyright © March 2013
BACKGROUND: Chronic hand dermatitis may have a significant detrimental effect on daily home-related and work-related activities, and quality of life (QOL). Clobetasol propionate foam, 0.05%, is indica...
Read MoreThe Role of a Midpotency Topical Corticosteroid and the Clinical Relevance of Formulation Characteristics in the Management of Commonly Encountered Eczematous and Inflammatory Dermatoses in Adults and Children:Focus on the Pharmacologic Properties of Clocortolone Pivalate 0.1% Cream
February 2013 | Volume 12 | Issue 2 | Supplement Individual Articles | 5 | Copyright © February 2013
Midpotency topical corticosteroids (TCSs) are frequently used for the treatment of common eczematous and inflammatory skin disorders in both adults and children. There are several commercially availab...
Read MoreClocortolone Pivalate: A Topical Corticosteroid With a Unique Structure
February 2013 | Volume 12 | Issue 2 | Supplement Individual Articles | 3 | Copyright © February 2013
Randomized, Controlled, Evaluator-Blinded Studies Conducted to Compare the Efficacy and Tolerability of 3 Over-the-Counter Acne Regimens in Subjects With Mild or Moderate Acne
February 2013 | Volume 12 | Issue 2 | Original Article | 180 | Copyright © February 2013
Background: Acne vulgaris is a common dermatologic disease that most frequently affects adolescents and young adults. Over-the-counter (OTC) acne treatment regimens are increasingly being used ...
Read MoreComparative Study of the Efficacy and Tolerability of a Unique Topical Scar Product vs White Petrolatum Following Shave Biopsies
January 2013 | Volume 12 | Issue 1 | Original Article | 86 | Copyright © January 2013
An excess of 70 million cutaneous surgical procedures are conducted annually in the United States that may result in scarring. Skin scars are a normal outcome of the tissue repair process. However, in...
Read MoreThe Treatment of Inflammatory Facial Dermatoses With Topical Corticosteroids: Focus on Clocortolone Pivalate 0.1% Cream
October 2012 | Volume 11 | Issue 10 | Original Article | 1194 | Copyright © October 2012
Objective: Study results evaluating the efficacy and safety of clocortolone pivalate 0.1% cream in the treatment of adults, young children, and infants with inflammatory facial dermat...
Read MoreHistologic Improvement in Photodamage After 12 Months of Treatment With Tretinoin Emollient Cream (0.02%)
September 2012 | Volume 11 | Issue 9 | Original Article | 1036 | Copyright © September 2012
Background and Objective: Topical retinoids, such as tretinoin, have been established as the gold standard for the treatment of photodamaged skin. This was a single-center, open-label, single-...
Read MoreTransepidermal Water Loss (TEWL) and Corneometry With Hydrogel Vehicle in the Treatment of Atopic Dermatitis: A Randomized, Investigator-Blind Pilot Study
February 2012 | Volume 11 | Issue 2 | Original Article | 181 | Copyright © February 2012
Disruption of the epidermal barrier, as indicated by a reduction in skin hydration and an increase in transepidermal wat...
Read MoreSafety and Efficacy Evaluation of Tretinoin Cream 0.02% for the Reduction of Photodamage: A Pilot Study
January 2012 | Volume 11 | Issue 1 | Original Article | 83 | Copyright © January 2012
Background: Clinical studies as well as histologic data maintain that tretinoin improves the appearance of photodamage; however, the long-term benefits of tretinoin 0.02% in moderate to severe ...
Read MoreTreatment of Mild-to-Moderate Chronic Hand Dermatitis With Clobetasol Propionate 0.05% EF Foam: Results From an Open-Label Study
December 2011 | Volume 10 | Issue 12 | Original Article | 1398 | Copyright © December 2011
Objective: To assess the safety and efficacy of clobetasol propionate 0.05% emulsion formulation (EF) foam in sub...
Read MoreCommentary: Doxycycline vs. Minocycline for the Management of Acne
September 2011 | Volume 10 | Issue 9 | Editorials | 966 | Copyright © September 2011
Doxycycline vs. Minocycline for the Management of Acne
September 2011 | Volume 10 | Issue 9 | Editorials | 965 | Copyright © September 2011
Topical Calcipotriene 0.005% and Betamethasone Dipropionate 0.064% Maintains Efficacy of Etanercept After Step-Down Dose in Patients With Moderate-to-Severe Plaque Psoriasis: Results of an Open Label Trial
August 2011 | Volume 10 | Issue 8 | Original Article | 878 | Copyright © August 2011
Etanercept is approved for the treatment of plaque psoriasis at a subcutaneous (SC) dosage of 50 mg twice-weekly for three months, followed by 50 mg SC once-weekly thereafter. It is of note, however,...
Read MoreEfficacy and Safety of Azelaic Acid (AzA) Gel 15% in the Treatment of Post-Inflammatory Hyperpigmentation and Acne: A 16-Week, Baseline-Controlled Study
June 2011 | Volume 10 | Issue 6 | Original Article | 586 | Copyright © June 2011
Although there are few differences in the incidence and pathophysiology of acne across various races and ethnicities, there is some evidence that black patients may have larger sebaceous glands and in...
Read MoreHarnessing the Anti-inflammatory Effects of Topical Dapsone for Management of Acne
June 2010 | Volume 9 | Issue 6 | Original Article | 667 | Copyright © June 2010
Data continue to establish the role of inflammation, not only in the pathogenesis of acne but also in the development of its most devastating sequelum, scarring. Although topical therapy is preferred...
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