Oats in Skincare

Welcome to the JDD Oats in Skincare Educational Resource Center. JDD is pleased to present a variety of evidence-based educational resources discussing the role of colloidal oatmeal in the management of cutaneous conditions. Materials presented will review the efficacy, safety, and expansive applications of colloidal oatmeal in skin care. Please bookmark this page and visit often to receive additional resources on the use of oats in the management of skin disorders and maintenance of healthy skin.

Editor's Recommendation

Natural Ingredients in Atopic Dermatitis and Other Inflammatory Skin Disease

Active naturals in dermatology have been experiencing a renaissance. Many of the naturals that have been known for centuries to be effective for various skin conditions have now been scientifically validated with the unraveling of the pathophysiology behind their medicinal mechanism.

Anti-Inflammatory Activities of Colloidal Oatmeal (Avena sativa) Contribute to the Effectiveness of Oats in Treatment of Itch Associated With Dry, Irritated Skin

Oat (Avena sativa) in colloidal form is a centuries-old topical treatment for a variety of skin conditions, including skin rashes, erythema, burns, itch, and eczema; however, few studies have investigated the exact mechanism of action for the anti-inflammatory activity of colloidal oatmeal.

Articles

Efficacy of a Hand Regimen in Skin Barrier Protection in Individuals With Occupational Irritant Contact Dermatitis

BACKGROUND: Occupational irritant contact dermatitis (OICD) is a dif cult and hard to manage condition. It occurs more frequently in certain occupations where contact with harsh chemicals, use of alcohol-based disinfectants, and frequent hand washing heightens the risk. Treatment for OICD includes patient education in addition to physical, topical, and systemic therapies. 

Exogenous Factors in Skin Barrier Repair (November) Colloidal Oatmeal (Avena Sativa) Improves Skin Barrier Through Multi-Therapy Activity

Oats (Avena sativa) are a centuries-old topical treatment for a variety of skin barrier conditions, including dry skin, skin rashes, and eczema; however, few studies have investigated the actual mechanism of action for the skin barrier strengthening activity of colloidal oatmeal. Four extracts of colloidal oatmeal were prepared with various solvents and tested in vitro for skin barrier related gene expression and activity. Extracts of colloidal oatmeal were found to induce the expression of genes related to epidermal differentiation, tight junctions and lipid regulation in skin, and provide pH-buffering capacity. Colloidal oatmeal boosted the expression of multiple target genes related to skin barrier, and resulted in recovery of barrier damage in an in vitro model of atopic dermatitis. 

Colloidal Oatmeal Part II: Atopic Dermatitis in Special Populations and Clinical Efficacy and Tolerance Beyond Eczema Article: Effects of Colloidal Oatmeal Topical Atopic Dermatitis Cream on Skin Microbiome and Skin Barrier Properties

Colloidal oatmeal has a diverse array of applications, clinical benefits, and uses beyond atopic dermatitis. First and foremost, it has been shown to be of benefit in the treatment of atopic dermatitis in skin of color. It has also been shown to be of benefit in the treatment of hand dermatitis, xerosis, psoriasis, skin manifestations of diabetes, and in the treatment of cutaneous adverse effects associated with oncologic therapies. In Part II of this 2-part series, we examine the efficacy, safety, and expansive clinical applications of colloidal oatmeal.

Colloidal Oatmeal (Avena Sativa) Improves Skin Barrier Through Multi-Therapy Activity

Oats (Avena sativa) are a centuries-old topical treatment for a variety of skin barrier conditions, including dry skin, skin rashes, and eczema; however, few studies have investigated the actual mechanism of action for the skin barrier strengthening activity of colloidal oatmeal.

Mechanism of Action and Clinical Benefits of Colloidal Oatmeal for Dermatologic Practice

Colloidal oatmeal has a long history of beneficial use in dermatology. It is a natural product that has an excellent safety record and has demonstrated efficacy for the treatment of atopic dermatitis, psoriasis, drug-induced rash and other conditions.

Anti-Inflammatory Activities of Colloidal Oatmeal (Avena Sativa) Contribute to the Effectiveness of Oats in Treatment of Itch Associated With Dry, Irritated Skin

Oat (Avena sativa) in colloidal form is a centuries-old topical treatment for a variety of skin conditions, including skin rashes, erythema, burns, itch, and eczema; however, few studies have investigated the exact mechanism of action for the anti-inflammatory activity of colloidal oatmeal.

Colloidal Oatmeal: History, Chemistry and Clinical Properties

Oatmeal has been used for centuries as a soothing agent to relieve itch and irritation associated with various xerotic dermatoses. In 1945, a ready to use colloidal oatmeal, produced by finely grinding the oat and boiling it to extract the colloidal material, became available.

A Randomized Controlled Clinical Study to Evaluate the Effectiveness of an Active Moisturizing Lotion with Colloidal Oatmeal Skin Protectant Versus Its Vehicle for the Relief of Xerosis

Xerosis is a common skin condition, occurring most often in the winter and in low relative humidity, which results in loss of moisture, cracking, and desquamation. Many emollient creams and lotions are available for use as preventive moisturizers. However, few controlled experiments have been published comparing the efficacy of active moisturizing products versus the vehicle used to deliver the products to the skin. Therefore, we conducted this randomized, double-blind, controlled clinical study to objectively compare a commercially available moisturizing product against its own vehicle. The active colloidal oatmeal moisturizer used in this study showed significant benefits versus its vehicle control in several dermatological parameters used to measure skin dryness.

Understanding the Complexities of the Stratum Corneum: Considerations and Strategies for Skin Barrier Maintenance

As the rst point of contact with a potentially drying external environment, the primary function of the stratum corneum (SC) is to limit evaporative water loss from the aqueous interior. Yet this is just one of many functionalities conferred by this unique barrier, also protecting against mechanical insults, the assault of foreign chemicals, and microorganisms, and even serving as the rst inherent defense against ultraviolet radiation. Beyond

Stratum Corneum Abnormalities and Disease- Affected Skin: Strategies for Successful Outcomes in Inflammatory Acne

Stratum corneum (SC) abnormalities are associated with disease-affected skin conditions such as inflammatory acne. Current topical acne treatment options including benzoyl peroxide and retinoids can worsen the barrier dysfunctions by increasing transepidermal water loss, depleting SC vitamin E levels, and relatively decreasing SC thickness. However, strategies exist to employ these treatments in a more effective manner and lessen barrier function disruption including use of less irritating vehicles or concomitant application of moisturizers.

A 1% Colloidal Oatmeal Cream Alone is Effective in Reducing Symptoms of Mild to Moderate Atopic Dermatitis: Results from Two Clinical Studies

Atopic dermatitis (AD), a chronic skin condition characterized by pruritus, inflammation, and acute are-ups of eczematous lesions over dry skin,1 affects approximately 15% to 20% children and approximately 1% to 3% adults worldwide,2 with slightly higher rates of incidence in the United States (children, 10%–25%; adults, 3%–5%).3,4 The wide range of clinical manifestations, the visible nature of the disease, and the intense itching associated with sleep disturbances, significantly affects patients’ quality of life and is a burden on healthcare resources.4

Noteworthy

Mechanism of Action and Clinical Benefits of Colloidal Oatmeal for Dermatologic Practice

Colloidal oatmeal has a long history of beneficial use in dermatology. It is a natural product that has an excellent safety record and has demonstrated efficacy for the treatment of atopic dermatitis, psoriasis, drug-induced rash and other conditions. In recent years, in vitro and in vivo studies have begun to elucidate the multiple mechanisms of action of naturally derived colloidal oatmeal. Evidence now describes its molecular mechanisms of anti-inflammatory and antihistaminic activity. The avenanthramides, a recently described component of whole oat grain, are responsible for many of these effects. Studies have demonstrated that avenanthramides can inhibit the activity of nuclear factor κB and the release of proinflammatory cytokines and histamine, well known key mechanisms in the pathophysiology of inflammatory dermatoses. Topical formulations of natural colloidal oatmeal should be considered an important component of therapy for atopic dermatitis and other conditions and may allow for reduced use of corticosteroids and calcineurin inhibitors

The Basic Science of Natural Ingredients

Herbal products have steadily gained popularity as alternatives to conventional, synthetic medications and are sought after by patients for the treatment of chronic dermatologic diseases and for cosmeceutical use. The production and distribution of botanical extracts is largely unregulated and therefore extensive research into their mechanism of action, safety, physiologic stability, and optimal dosing has been overlooked.

Stratum Corneum Abnormalities and Disease- Affected Skin: Strategies for Successful Outcomes in Inflammatory Acne

Stratum corneum (SC) abnormalities are associated with disease-affected skin conditions such as inflammatory acne. Current topical acne treatment options including benzoyl peroxide and retinoids can worsen the barrier dysfunctions by increasing transepidermal water loss, depleting SC vitamin E levels, and relatively decreasing SC thickness. However, strategies exist to employ these treatments in a more effective manner and lessen barrier function disruption including use of less irritating vehicles or concomitant application of moisturizers. Patients also play a role in the outcome of their skin barrier function based on their compliance and administration technique. By increasing patient compliance and proper application of treatments, patient skin barrier function can improve. Additionally, future treatments are on the horizon that may customize acne therapy at a molecular level.

Advertisement

Webinars

What You Need to Know About Eczema in Diverse Skin Tones: From Diagnosis to Daily Management

The objectives of this webinar are to learn the nuances in the presentation, diagnosis and treatment of your skin of color patients with atopic dermatitis and to understand the role of colloidal oatmeal in the treatment plan.

The Role of Colloidal Oatmeal in Managing Eczema and Beyond

This webinar highlights the data supporting the mechanism of action of oat in emollients as well as clinical efficacy and safety of its use in atopic dermatitis and beyond.

Watch Now

Supplements

The Biological Impact of Oats: Eczema and Beyond

The objective of this Supplement is to highlight the data supporting the use of colloidal oatmeal in the treatment of atopic dermatitis and other skin conditions resulting from an impaired skin barrier or inflammation.  Clinical efficacy and tolerance will be highlighted.

Read More

Podcasts

Support the (On)cause: A Practical Review of Supportive Oncodermatology

Cancer sucks, plain and simple. What is often overlooked is that the life saving/altering therapies often come with substantial baggage adding to this proclamation with skin, hair, and nail adverse events significantly impacting quality of life and even treatment course.
Enter supportive oncodermatology, and along with it the mastermind behind this rapidly emerging field, Dr. Mario Lacouture, Professor and Director of the Oncodermatology Program in the Dermatology Service, Department of Medicine, at Memorial Sloan Kettering Cancer Center in New York City.
Dr. Lacatoure joins podcast host Dr. Adam Friedman to discuss the array of cutaneous clusters that not only can, but are almost expected to occur during cancer therapy. Learn how even simple OTC products can contribute to both ameliorating and even preventing some of these sequelae. Understand how you (yeah, I’m talkin’ to you) can make an extraordinary impact in these patients’ lives. Tune in to this podcast to support your supportive oncoderm fund of knowledge.
This podcast was supported by Johnson & Johnson Consumer Inc.
Listen Now