Issue Archive
December 2022 | Volume 21 | Issue 12
Original Articles
Emerging Intralesional Treatments for Plantar Warts: A Systematic Review
Background: Therapies for plantar warts remain subjective and unclear, which has led to continual pursuit of an optimal treatment. As a consequence, many intralesional therapies have emerged over the ...
Read MoreA Randomized, Double-Blind, Split-Face Study of Topical Silymarin vs 2% Hydroquinone Cream in Melasmas
Background: Hydroquinone is effective in melasma treatment, but side effects may limit its use. Silymarin cream may be a safer alternative. Objective: To compare the efficacy of 1.4% silymarin with 2%...
Read MoreAn Analysis of Alopecia Related Content on Instagram and TikTok
Background: Social media platforms continue to grow in popularity and have become common sources of medical information and education for patients struggling with hair loss.
Objective: We sought...
Read MoreThe Effect of an Autologous Protein-Based Topical Serum on Cutaneous Burns
Background: Burns are skin lesions that can be life-threatening. Platelet-rich plasma (PRP) is growing as an effective alternative for the management of burns. The objective of this study was to asses...
Read MoreImmune-Response Modifiers: Characteristics of High-Volume Prescribers
Background: Oral small molecules (OSM) and biologic immune response modifier drugs share some indications for use but have a different side effect profiles. As such, certain providers may be more like...
Read MoreClinical Utility of Dermoscopy and 31-Gene Expression Profiling by Dermatology Providers in Melanoma Management Care
Objective: A 31-gene expression profile (31-GEP) test that predicts metastatic risk in patients with cutaneous malignant melanoma (CMM) has previously been validated and is available for clinical use....
Read MoreJAK Inhibitor Safety Compared to Traditional Systemic Immunosuppressive Therapies
Dermatologists treating atopic dermatitis are interested in the safety profile of the recently available JAK inhibitors, upadacitinib and abrocitinib, especially after they received boxed safety warni...
Read MoreA Topical Combination Regimen of Benzoyl Peroxide and Retinol Moisturizer for Mild to Moderate Acne
Topical therapies, in many cases over-the-counter (OTC) formulations, are available for the treatment of acne, including benzoyl peroxide (BPO), salicylic acid, and retinoids. While these agents...
Read MoreRecent Advances in Melanoma Tumorigenesis
Melanoma is a tumor that continues to increase in both the number of cases presenting and mortality. Patients with disease that has spread beyond the cutaneous boundary still suffer from significant m...
Read MoreBacteriophages: An Alternative to Combat Antibiotic Resistance?
Background: Antibiotic resistance has become one of the largest pitfalls of modern medicine, and this has fueled the search for a safe and effective alternative. Of these alternatives, bacteriophage (...
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Features
An Up-to-Date Approach to the Management of Seborrheic Dermatitis
Seborrheic dermatitis (SD) is a chronic, relapsing, inflammatory dermatosis with ambiguous pathophysiology of overcolonization of Malassezia combined with predisposing factors including sebocyte activ...
Read MoreA Potential Alternative Treatment for Vitiligo: An Observational Study on Tacrolimus 0.3% Lotion
Vitiligo is a complex multifactorial disorder of depigmentation affecting 0.5 to 2% of the world's population without specific gender or racial prevalence.1 Though no treatments are FDA approved to re...
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Case Reports
Syringotropic Mycosis Fungoides: A Variant of Folliculotropic or a Distinct Subtype of Adnexotropic Mycosis Fungoides?
Mycosis fungoides (MF) is a slowly progressive form of cutaneous T-cell lymphomas (CTCL). MF is classified into 4 subtypes including folliculotropic MF (FMF). Infiltration of both hair follicles and e...
Read MoreA Case of Successful Management of Adult-Onset Linear IgA Bullous Disease With Sulfasalazine During the COVID-19 Pandemic
Linear IgA bullous disease (LABD) is a rare, acquired, autoimmune, pruritic, and blistering skin condition. Dapsone is a first line treatment option, however, there are limited options if this fails, ...
Read MoreNovel Regimen of IL-17A Inhibitor Secukinumab for the Remission of Severe Hidradenitis Suppurativa: Case Report
Hidradenitis suppurativa (HS) is a morbid, recurrent skin condition that presents a major challenge to clinical therapy. Investigation into the pathogenesis of HS has implicated local and systemic pro...
Read MoreRefractory Alopecia Areata and Vitiligo Responding to Tofacitinib Monotherapy
Background: In the last several years, oral tofacitinib has become an increasingly utilized off-label treatment option for immune-mediated skin conditions such as alopecia areata (AA), vitiligo, plaqu...
Read MoreTreatment of Reactive Keratoacanthomas with Acitretin Following Multiple Excisions and Mohs Surgery for Recurrent Squamous Cell Carcinoma
Surgical intervention is seen as the gold standard in the treatment of Squamous cell carcinoma. Yet, in cases of recurrence, repeated surgical procedures may unwittingly foment the rise of reactive ke...
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Departments
FULL SUPPLEMENT: Why Care About Skin Care When Managing Acne?
A specific skincare regimen incorporating both a designated cleanser and moisturizer is reviewed with study results reported from 44 adult patients with AV. The designated cleanser is Cetaphil Gentle ...
Read MoreFULL SUPPLEMENT: Status Update On Truncal Acne
Truncal acne, while similar to facial acne, requires a dedicated assessment due to its nuanced response to therapies and psychosocial burden. There has been an increased awareness of truncal acne as a...
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Supplements
SUPPLEMENT INDIVIDUAL ARTICLE: Bridging the Gap: Optimizing Skin Care in Acne Treatment
To optimize the treatment of dermatologic diseases, one must recognize the interplay between maintaining the function of the skin barrier and utilizing topical medications which often disrupt the form...
Read MoreSUPPLEMENT INDIVIDUAL ARTICLE: Optimizing Skin Care in Acne Treatment - Evaluation of a Designated Cleanser and Moisturizer Regimen With Improvement in Clinical Outcomes
Acne vulgaris (AV) is one of the most common skin disorders encountered in outpatient dermatology practice worldwide, commonly affecting adolescents, but also pre-teens and postadolescent adults of an...
Read MoreSUPPLEMENT INDIVIDUAL ARTICLES: "Vehicles Matter" in the Treatment of Truncal Acne
Among the general population and arguably among most dermatologists, the word acne calls to mind images of a teenager with papules and pustules on the face. Yet, we know that acne is not just a diseas...
Read MoreSUPPLEMENT INDIVIDUAL ARTICLES: Update on Truncal Acne: A Review of Treatments for a Neglected Disease and the Re-Emergence of Tazarotene
Acne vulgaris of the trunk carries with it a major psychosocial impact and an unmet need for adequate management. Approximately 50% of patients with facial acne also exhibit involvement of the back, c...
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