FULL SUPPLEMENT: Status Update On Truncal Acne

December 2022 | Volume 21 | Issue 12 | SF3446181 | Copyright © December 2022


Published online November 30, 2022

Abstract
Truncal acne, while similar to facial acne, requires a dedicated assessment due to its nuanced response to therapies and psychosocial burden. There has been an increased awareness of truncal acne as a neglected entity, and recent interventional studies have begun to focus on efficacy endpoints of the chest, back, and upper arms. While there have been some. clinical trials that examined treatments for truncal acne, more research is needed. Furthermore, reformulation of efficacious drugs such as tazarotene in optimized vehicles for topical application is a promising therapeutic approach.
In this supplement:

“Vehicles Matter” in the Treatment of Truncal Acne
Among the general population and arguably among most dermatologists, the word acne calls to mind images of a teenager with papules and pustules on the face. Yet, we know that acne is not just a disease of adolescence, and it is not limited to the face.

Read the article here.

Update on Truncal Acne: A Review of Treatments for a Neglected Disease and the Re-Emergence of Tazarotene
Acne vulgaris of the trunk carries with it a major psychosocial impact and an unmet need for adequate management. Approximately 50% of patients with facial acne also exhibit involvement of the back, chest, and/or upper arms. The trunk poses a therapeutic challenge given its occlusion by clothing, the tendency for mechanical rubbing, a sebum physiology that differs from the face, as well as the fact that there is a large surface area for topical therapies to cover. Furthermore, truncal acne is underreported for a variety of reasons such as cultural barriers, sentiments of embarrassment, and prioritization of facial acne. To date, few medications have been studied specifically for truncal acne. In this article, an updated review of truncal acne and available therapies is provided. The most recent evidence for tazarotene, a third-generation retinoid previously approved for psoriasis and facial acne vulgaris over two decades ago, is also reviewed and compared to trifarotene, a fourth-generation retinoid that is the only approved tropical retinoid for both facial and truncal acne.

Read the article here.