Current Issue
April 2025 | Volume 24 | Issue 4
Editorials
Original Articles
Clinical Utility of TRPV1 Modulation for Skincare Sensitivity
The Transient Receptor Potential Vanilloid 1 (TRPV1) protein, originally recognized for its role in modulating peripheral sensory neurons and transmitting pain and itch signals, has been increasingly ...
Read MoreArtificial Intelligence-Generated Educational Curriculum on Facial Neurotoxin Injections: Assessment of Educational Content, Curriculum Structure, and Course Logistics
Background: Large language models (LLMs) have revolutionized the way physicians access and leverage artificial intelligence (AI). The potential role of AI in facilitating aesthetic medical education ...
Read MoreTop Chief Complaints and Diagnoses for Outpatient Dermatology Patients of Color
Background: By 2044, people with skin of color (SOC) in the United States are projected to become the majority of the population, yet research and practice gaps remain regarding the dermatologic condi...
Read MoreImprovement in Skin Moisturization and Lack of Barrier Damage Following Treatment With Clascoterone Cream 1%
Background: Topical medications commonly prescribed for the treatment of acne vulgaris may be limited by application-site dryness, which can result in skin barrier damage. This study aimed to evaluate...
Read MoreThe Utility of Oral Polypodium Leucotomos Extract for Dermatologic Diseases: A Systematic Review
Background: Polypodium leucotomos extract (PLE), a fern plant product with strong anti-inflammatory and immunomodulatory properties, has been employed to reduce photoaging and skin cancer. PLE may als...
Read MoreThe State of the Clinical Management Union: A Cross-Sectional Survey of Persons With Hidradenitis Suppurativa
Background: Hidradenitis suppurativa (HS) is a chronic autoinflammatory condition notable for a high psychosocial burden on patients. This burden is theorized to be linked to patient dissatisfaction d...
Read MoreRituximab in the Treatment of Epidermolysis Bullosa Acquisita: A Systematic Review of the Literature
Epidermolysis bullosa acquisita (EBA) is a rare autoimmune disorder characterized by blistering of the skin and mucous membranes. Current pathophysiology implicates autoantibodies targetin...
Read MoreAn Algorithm Integrating Acneceuticals into the Management of Acne Vulgaris
Background: Acne vulgaris is a common, chronic cutaneous disorder with numerous efficacious prescription and procedural treatments. Therapy, however, is hampered by medication intolerability and compr...
Read MoreAn Innovative Cream Improves Signs and Symptoms of Dermatoporosis in Patients Aged 65 and Over
Background: There is increasing recognition of dermatoporosis - a condition of chronic cutaneous fragility of aging skin seen primarily in older adults. Dermatoporosis can be characterized by white ps...
Read MoreRacial and Ethnic Representation in Atopic Dermatitis Clinical Trials
Atopic dermatitis (AD) is a chronic inflammatory skin disorder afflicting approximately 31.6 million people in the United States, with a disproportionate impact on racial and ethnic minori...
Read MoreSingle-Center, Open-Label Study Study to Evaluate Improvement of Hair Appearance With Novel Hair Growth Serum
Background: REVIVV® is a topical hair growth serum with a proprietary formula of botanicals that addresses multiple factors involved in hair loss pathophysiology. This open-label, prospective, sin...
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Features
Off-Label Management Strategies for Generalized Granuloma Annulare: What's New?
Effects of a Moisturizer Containing Colloidal Oatmeal and Filaggrin Technology on Staphylococcus Species In Vitro
The pathophysiology of atopic dermatitis (AD) is multifactorial, with genetic predisposition, environmental exposures, and dysbiosis of the skin microbiome all associated with disease activity. Coloni...
Read MoreAcetyl Hexapeptide-8 as a Topical Alternative to Botulinum Toxin: A Review of the Literature
A Retrospective Comparative Analysis of Cutaneous Adverse Reactions in GLP-1 Agonist Therapies
Glucagon-like peptide-1 (GLP-1) agonists are used to treat type 2 diabetes mellitus (T2DM) and have recently gained approval and popularity for treating obesity and weight loss. There is a lack of dat...
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Case Reports
Improvement of Hailey-Hailey Disease Following Administration of Dupilumab
Hailey-Hailey disease (HHD) is a rare, chronic skin disorder characterized by recurrent inflammatory plaques with painful blisters, erosions, and macerations. We report a case of a 40-year-old female ...
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Departments
FULL SUPPLEMENT: United States Cutaneous Oncodermatology Management (USCOM ) V: A Multidisciplinary-Guided Algorithm for Preventing and Managing Cutaneous Hormonal Therapy-Related Adverse Events in Cancer Patients
Although cancer incidence continues to rise, advancements in treatment options have contributed to the decline in cancer mortality.1,3 Hormonal therapy is a mainstay treatment for the management of ho...
Read MoreFULL SUPPLEMENT: Incorporating Cosmeceuticals in In-Office Aesthetic Procedures for Skin of Color
Common signs of skin aging include wrinkles, fine lines, and pigmentary disorders. Patients with skin of color present with unique dermatologic challenges due to differences in how skin conditions man...
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Supplements
INDIVIDUAL ARTICLE: USCOM V: A Practical Algorithm for the Prevention and Treatment of Cutaneous Side Effects of Hormonal Cancer Therapy
Introduction: In 2024, over 2 million patients will be diagnosed with cancer in the United States, with prostate cancer and breast cancer representing the leading diagnoses in men and women, respectiv...
Read MoreINDIVIDUAL ARTICLE: Breaking Barriers: Advancing Cosmeceuticals and Integrated Skincare for Skin of Color
Common signs of skin aging include wrinkles, fine lines, and pigmentary disorders. Patients with skin of color present with unique dermatologic challenges due to differences in how skin conditions man...
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