Temporal Association of Herpes Zoster Eruption Post-Aminolevulinic Acid Hydrochloride Photodynamic Therapy for Actinic Keratoses

August 2017 | Volume 16 | Issue 8 | Case Reports | 817 | Copyright © August 2017

Katie Manno MDa and Joel L. Cohen MD FAADb,c,d

aJohn H. Stroger, Jr. Hospital of Cook County, Chicago, IL bAboutSkin Dermatology and Derm Surgery, Greenwood Village and Lone Tree, CO cUniversity of Colorado, Department of Dermatology, Aurora, CO dUniversity of California Irvine, Department of Dermatology, Irvine, CA


Herpes zoster is a common and painful disease caused by the reactivation of the varicella-zoster virus with a higher incidence and severity associated with increasing age as well as compromised immune status. Acute inciting events for this eruption are not always known, but can include illness, stress, and mechanical injury. Photodynamic therapy (PDT) is a widely used treatment modality for precancerous skin lesions that has not been previously associated with provoking a herpes zoster outbreak. We present a case of herpes zoster eruption occurring after PDT for actinic keratoses in a patient with Non-Hodgkin Lymphoma (NHL).

J Drugs Dermatol. 2017;16(8):817-818.