Plantar Wart Treatment with Combination Imiquimod and Salicylic Acid Pads

February 2003 | Volume 2 | Issue 1 | Case Reports | 70 | Copyright © February 2003

Stephen B. Tucker, MD; Asra Ali, MD and Brian L. Ransdell, BA

Treatment of plantar warts is often difficult and may be painful, often employing destructive treatment modalities. We report the successful treatment of a patient with a large plantar wart using Imiquimod 5% cream under occlusion with a 40% salicylic acid pad. This combination treatment modality likely allows successful delivery of Imiquimod through the thick skin on the plantar surface. Once penetrated, an anti-viral state is created by upregulating specific cytokines to eradicate the human papilloma virus (HPV).