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Dec 10
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Systemic Medications of Dermatological Importance in COVID-19

By No Comments
INTRODUCTIONIn light of the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infection being declared a pandemic by World Health Organization (WHO), the International Clinical Trials Registry Platform of WHO has…
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Dec 10
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The Impact of Pharmacy Benefit Managers on Drug Pricing

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INTRODUCTIONWhat is behind the price of a medication that we see today? Who is responsible for the obstacles that prevent patients from getting on life changing medications? In other words,…
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Dec 10
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Safety and Effectiveness of Hyaluronic Acid Fillers With Lidocaine for Full-Face Treatment in Asian Patients

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INTRODUCTIONEffectiveness and safety of Restylane® Lidocaine (HAR; Galderma, Uppsala, Sweden) and Restylane Lyft Lidocaine (HARL), manufactured using the NASHAâ„¢ technology, have been evaluated in clinical studies mostly performed in North…
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Dec 10
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Efficacy and Safety of Calcipotriene 0.005%/Betamethasone Dipropionate 0.064% Foam With Apremilast for Moderate Plaque Psoriasis

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INTRODUCTIONPsoriasis is a chronic inflammatory skin disease.1,2 While there is currently no cure for psoriasis, treatments are available that are aimed at controlling the disease and improving the patient’s quality…
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Dec 10
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Cutaneous Manifestations of EGFR-Inhibitors in African Americans and Treatment Considerations

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INTRODUCTIONTargeted therapies in particular epidermal growth factor (EGFR)-inhibitors have emerged as the primary therapy in advanced solid tumor malignancies including colorectal, pancreas, head and neck cancers, and non-small cell lung…
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Dec 10
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Human Pharmacokinetics and Safety of Subcutaneous Collagenase Clostridium Histolyticum in Women

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INTRODUCTIONCellulite is a localized alteration of skin topography (eg, dimpling) and affects 80% to 98% of postpubertal women of all ages and ethnicities.1,2 Although the pathophysiology of cellulite has not…
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Dec 10
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Efficacy and Safety of Intense Pulsed Light With a KTP/PDLlike Filter for the Treatment of Facial Telangiectasias

By No Comments
INTRODUCTIONTelangiectasias are small blood vessels, typically measuring 0.1 to 1.0 mm in diameter, which may be of venular, capillary, or arteriolar origin.1,2 Telangiectasias develop secondary to a variety of factors…
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Dec 10
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Safety, Pharmacokinetics, and Efficacy of Efinaconazole 10% Topical Solution for Onychomycosis Treatment in Pediatric Patients

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INTRODUCTIONOnychomycosis—a chronic and recurring fungal infection of the fingernails or toenails—can occur in children, ranging in prevalence from 0.35%–5.5% worldwide.1 Though less common in children than adults,1 onychomycosis has been…
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Dec 10
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Biological Effects of Hyaluronic Acid-Based Dermal Fillers and Laser Therapy on Human Skin Models

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INTRODUCTIONInjection of hyaluronic acid (HA) dermal fillers is one of the most frequently performed aesthetic procedures.1 HA fillers exist in many different formulations differing in HA concentration, particle size and…
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Dec 10
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Randomized, Double-Blinded, Split-Face Study Comparing the Efficacy and Tolerability of Two Topical Products for Melasma

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INTRODUCTIONMelasma is a common, acquired disorder of skin hyperpigmentation that characteristically presents with symmetric brown macules and patches on the cheeks, forehead, and chin. The highest prevalence is seen in…
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Dec 10
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Prospective Analysis in Patients With HAE Under Prophylaxis With Lanadelumab: A Real-life Experience

By No Comments
INTRODUCTIONPatients suffering from the bradykinin-induced genetic disease hereditary angioedema (HAE) show recurrent swelling of subcutaneous and submucosal structures. The attacks can affect almost every part of the body and may…
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Dec 10
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Hyaluronidase in Dermatology: Uses Beyond Hyaluronic Acid Fillers

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BACKGROUNDHyaluronidase is an enzyme used in ophthalmic surgery and dermatology. Its use is well-established and is the standard approach in dissolving Hyaluronic acid (HA) fillers (off-label) both in overcorrection and…
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