INTRODUCTIONThe cannabis plant, cannabis sativa, and its derivatives have been used in medicinal preparations for millennia to treat pain, nausea, and epilepsy. Recent research has identified a number of other…
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INTRODUCTIONPsoriasis is a chronic and persistent, immune-mediated disease that affects approximately 2% of the population 1-3. Most patients have mild to moderate plaque psoriasis, which despite its limited cutaneous involvement,…
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INTRODUCTIONPsoriasis is a common chronic inflammatory disease as- sociated with numerous comorbidities, with a profound impact on patients’ quality of life. Assessing disease severity without biomarkers has led to the…
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INTRODUCTIONPsoriasis (PsO) is a chronic immune-mediated skin disorder characterized by erythematous, scaling plaques, which are often pruritic or painful. The prevalence of PsO in the United States is approximately 3.2%…
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INTRODUCTIONThe natural aging process, regardless of an individual’s genetic disposition and lifestyle, leads to a variety of skin manifestations such as dyschromias, change in pore size, lines, textural irregularities, loss…
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INTRODUCTIONHair thinning and loss is highly prevalent in the adult population. Estimates suggest that by age 50, approximately 50% of men will experience some degree of hair loss secondary to…
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INTRODUCTIONK-wires and metal pins are commonly used for exter- nal fixation in patients requiring provisional or definitive fixation.These pins protrude through the skin and create an avenue for migration of…
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INTRODUCTIONThis observation describes the presentation, histopatho- logic diagnosis, and treatment of a malignant proliferating trichilemmal tumor. Clinical PresentationA 38-year old female presented with a several-year history of an enlarging, firm,…
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INTRODUCTIONBehçet’s syndrome is an inflammatory disease characterized by aphthous oral ulcers and several systemic manifestations, which include genital ulcers, ocular disease, skin lesions, arthritis, and vascular disease. Recurrent oral ulcers…
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BiologicsBiologics are monoclonal antibodies (ie, infliximab, adalimumab, ustekinumab, dupilumab, etc.) or fusion proteins (ie, etanercept) that have activity in the extracellular space. Infliximab and adalimumab bind to tumor necrosis factor-α…
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INTRODUCTIONCutaneous B-cell lymphomas (CBCLs) are indolent lymphomas presenting in the skin. Primary CBCL is classified according to the WHO/EORTC into three types1: primary cutaneous marginal zone lymphoma (PCMZL), primary cutaneous…
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INTRODUCTIONRituximab, an anti-CD20 chimeric monoclonal antibody, has recently been granted FDA-approval for the treatment of pemphigus vulgaris (PV). While generally very effective, infrequently rituximab loses efficacy due to the development…
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