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Dec 10
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New Insight Into the Pathophysiology of Hair Loss Trigger a Paradigm Shift in the Treatment Approach

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INTRODUCTIONAndrogens, genetic susceptibility, chronic inflammation, oxidative stress, internal and external environmental triggers such as ultraviolet light, pollutants, aging, poor nutrition, as well as mediators of psycho-emotional stress (eg, cortisol and…
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Dec 10
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A Novel Multi-Targeting Approach to Treating Hair Loss, Using Standardized Nutraceuticals

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INTRODUCTIONNutraceuticals are an emerging category of beauty products and one of the fastest growing segments in the nutricosmetic market.1 This class of naturally derived therapeutics from food and botanicals contain…
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Dec 10
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New Insight Into the Multifactorial Pathophysiology of Hair Loss: Inflammation, Stress, and Follicle Biology Take Front Stage

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Dec 10
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Letters to the Editor: The Aesthetic

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Dec 10
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Upregulation of Extracellular Matrix Genes Corroborates Clinical Efcacy of Human Fibroblast-Derived Growth Factors in Skin Rejuvenation

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INTRODUCTIONImproved understanding of biochemical mechanisms of skin aging has resulted in the identification of key pathways of intervention to accelerate the reversal of skin aging.1 Growth factors, cytokines and other agents…
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Dec 10
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Lawrence Transfer Factor: Transference of Specific Immune Memory by Dialyzable Leukocyte Extract from a CD8+ T Cell Line

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INTRODUCTIONTransfer factor (TF), also known as LawrenceTF, is an immunologic concept developed by Sherwood Lawrence, a highly-decorated immunologist, the former chair of New York University’s Division of Infectious Disease and…
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Dec 10
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Combining Topical Psoriasis Treatment to Enhance Systemic and Phototherapy: A Review of the Literature

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INTRODUCTIONPsoriasis is a chronic inflammatory skin disease that is characterized by disfiguring, scaling, and erythematous plaques that can be painful or severely pruritic.1 In the United States, an estimated 7.4 million…
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Dec 10
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The Latest Drugs and Small Molecule Inhibitors for Skin and Hair

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INTRODUCTIONBiologic drugs are a novel class of pharmacological agents, isolated from a variety of natural sources, engineered to target specific mediators of inflammation. They represent the cutting-edge of biomedical research…
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Dec 10
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A Novel Multifactorial Approach to Developing Mild Laundry Detergents and Assessing Their Relative Mildness

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INTRODUCTIONDermatologists often recommend laundry detergents that are free of harsh chemicals, fragrances and dyes.1 New methodologies have enabled the development of a laundry detergent with a new level of mildness.…
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Dec 10
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Real-World Clinical Experience With Apremilast in a Large US Retrospective Cohort Study of Patients With Moderate to Severe Plaque Psoriasis

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INTRODUCTIONPsoriasis is a chronic, systemic inflammatory disease affecting 1% to 4% of the world’s population.1-3 Although treatment options for moderate to severe psoriasis have expanded in recent years, many patients…
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Dec 10
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Cost Per Additional Responder Associated With Ixekizumab and Etanercept in the Treatment of Moderate-to-Severe Psoriasis

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BACKGROUNDPsoriasis is a common immune disease characterized by thick scaly red lesions and systemic comorbidities. Psoriasis has an enormous effect on patients’ lives, reducing health-related quality of life to an…
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Dec 10
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A Systematic Review of Lower Lip Anatomy, Mechanics of Local Flaps, and Special Considerations for Lower Lip Reconstruction

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INTRODUCTIONThe lower lip is a complex structure with a significant functional and aesthetic role. There is extensive literature on the different surgical approaches for lower lip reconstruction driven by the…
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