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Dec 10
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The Basic Science of Natural Ingredients

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INTRODUCTION Herbal medicine, also referred to as botanical medicine and phytomedicine, has steadily gained popularity as an alternative to conventional, synthetic drug use.1 In 2007, 1 out of 4 adults…
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Dec 10
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Ustekinumab Treatment for Psoriasis in 119 Patients Maintained on Therapy for a Minimum of One Year: A Review

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INTRODUCTIONPsoriasis is a chronic and complex genetic immune-mediated disease affecting up to 2% of the US population.1 The pathogenesis of psoriasis stems from dysregulated inflammation, which leads to hyperproliferation of…
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Dec 10
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A Randomized, Double-Blinded Trial Evaluating the Efficacy and Tolerability of Vectical Ointment (Calcitriol 3 mcg/g Ointment) When Compared to Betamethasone Diproprionate Ointment (64 mg/g) in Patients With Nail Psoriasis

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INTRODUCTION Psoriasis is a chronic, incurable skin disease affecting millions of people worldwide. Nail abnormalities occur concomitantly in 50% of patients with psoriasis, with a lifetime incidence of 80% to…
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Dec 10
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Trends in Systemic Psoriasis Treatment Therapies from 1993 Through 2010

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INTRODUCTIONA 2004 study determined that the prevalence of diagnosed psoriasis was 3.15%, which is the equivalent of approximately 5 million adults, while the National Psoriasis Foundation estimates that the number…
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Dec 10
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A Randomized, Prospective, Sham-Controlled Study of Localized Narrow-Band UVB Phototherapy in the Treatment of Plaque Psoriasis

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INTRODUCTION Psoriasis is a chronic autoimmune disease that affects 2-3% of adults.1 Despite newer oral and injectable systemic treatment options, phototherapy remains prevalent in disease therapy. Ultraviolet-B (UVB) phototherapy involves…
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Dec 10
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The Use of Self-Administered Subcutaneous Methotrexate for the Treatment of Psoriasis

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INTRODUCTIONWith nearly 50 years of use, methotrexate is a mainstay of therapy for psoriasis. Appropriate patient selection and careful monitoring provides safe and reliable use for a reasonable cost.1-4 Methotrexate…
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Dec 10
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Tumor Necrosis Factor Inhibitor Therapy and Myocardial Infarction Risk in Patients With Psoriasis, Psoriatic Arthritis, or Both

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INTRODUCTION Psoriasis is a chronic skin condition affecting approximately 2-3% of the U.S. population and worldwide.1 About 15-40% of those with psoriasis also have psoriatic arthritis. Those with psoriatic arthritis…
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Dec 10
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Targeted Therapy for Cutaneous Oncology: A Review of Novel Treatment Options for Non-Melanoma Skin Cancer: Part I

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INTRODUCTIONAn evolving theme in the field of cutaneous oncology is the use of personalized or targeted therapy for the treatment of advanced disease. Targeted therapy is the identification of the…
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Dec 10
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Targeted Therapy for Cutaneous Oncology: A Review of Novel Treatment Options for Non-Melanoma Skin Cancer: Part II

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INTRODUCTIONAn evolving theme in the field of cutaneous oncology is the use of personalized or targeted therapy for the treatment of advanced disease. Targeted therapy is the identification of the…
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Dec 10
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The Science Behind Common Over-the-Counter Remedies Used in Dermatology

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INTRODUCTIONOur patients are inundated with information and misinformation about many over-the-counter products used for various dermatological conditions. Family remedies and folktales regarding the use of products to treat skin conditions…
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Dec 10
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How Suture Technique Affects the Cosmetic Outcome of Cutaneous Repairs

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INTRODUCTION Skin defects can be repaired via primary closure, secondary intention healing, local and distant flaps, skin grafts, application of natural and synthetic skin substitutes. Linear repair is usually preferred…
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Dec 10
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Safety and Effectiveness of Ustekinumab for Treatment of Moderate to Severe Psoriasis: A Prospective Study in a Clinical Setting

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INTRODUCTIONPsoriasis is a chronic immune-mediated skin disorder that affects 2% of the population. Moderate to severe forms of psoriasis require systemic treatment. The management of this condition with classic systemic…
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