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Dec 10
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Understanding, Avoiding, and Treating Potential Adverse Events Following the Use of Injectable Poly-L-Lactic Acid for Facial and Nonfacial Volumization

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Introduction Injection-related adverse events (AEs) may occur with the use of any injectable substance, including all currently commercially available fillers. The most common of these AEs include discomfort, bruising, edema,…
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Dec 10
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Satisfying Patient Expectations With Poly-L-Lactic Acid Soft Tissue Augmentation

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INTRODUCTION There has been significant growth in both patient interest and physician use of soft tissue augmentation in recent years, especially among younger patients. Patients’ motivation behind this increased interest…
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Dec 10
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Consensus Recommendations on the Use of Injectable Poly-L-Lactic Acid for Facial and Nonfacial Volumization

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Introduction Poly-L-lactic acid (PLLA) was approved for use in Europe in 1999. In the United States, it was approved by the Food and Drug Administration in 2004 for the treatment…
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Dec 10
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Treatment Options in Facial and Nonfacial Volumization: An Introduction to Poly-L-Lactic Acid

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Dec 10
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Heads Up for Scalp Melanoma

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It brings me great pleasure to introduce this edition of the JDD highlighting articles on skin cancer. I’d like to take this opportunity to make it personal – and share…
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Dec 10
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Defining Locally Advanced Basal Cell Carcinoma

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Basal cell carcinoma (BCC) is the most common human cancer.1 When detected early the vast majority of cases are successfully managed surgically, with 5-year cure rates exceeding 90%.2 Although rare,…
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Dec 10
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Two Recent JDD Articles Highlight Genome and Proteome Protection and Repair Strategies

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I thoroughly enjoyed reading the two articles by Drs. Emanuele and Spencer in your March Issue. The first article, “From DNA repair to proteome protection: new molecular insights for preventing…
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Dec 10
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A Retrospective Comparison Between Preoperative and Postoperative Breslow Depth in Primary Cutaneous Melanoma: How Preoperative Shave Biopsies Affect Surgical Management

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INTRODUCTION Histopathologic examination of preoperative biopsy specimens remains paramount in terms of diagnosing melanoma. Rates of diagnosing melanoma accurately from a purely clinical basis leave much to be desired, with…
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Dec 10
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Review of the Use of a Semisynthetic Bilaminar Skin Substitute in Dermatology and a Case Series Report of Its Utility in Mohs Surgery

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INTRODUCTIONBiobrane (Smith & Nephew, London, UK) is a biosynthetic wound dressing that has been widely used in burn treatment and as a skin graft donor site dressing.1,2 It has been…
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Dec 10
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Trends in the Outpatient Medication Management of Lupus Erythematosus in the United States

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INTRODUCTION Systemic lupus erythematosus (SLE) is the second most common autoimmune disorder amongst women of childbearing age after thyroid disease. SLE is challenging to manage as it affects the body…
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Dec 10
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Analysis of Body Regions and Components of PASI Scores During Adalimumab or Methotrexate Treatment for Patients With Moderate-to-Severe Psoriasis

By No Comments
The Psoriasis Area Severity Index (PASI) is the most commonly utilized and extensively validated tool to assess the severity of psoriasis and treatment effect, especially in clinical research.1,2 PASI quantitatively…
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Dec 10
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Update on the Immunological Mechanism of Action Behind Phototherapy

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INTRODUCTION Psoriasis, eczema and other immune-mediated skin diseases arise in the context of cutaneous inflammation.1 The majority of treatments for these conditions target the effector arm of the immune response,…
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