An estimated 10% of the US population has at least one tattoo, with up to one fourth in those younger than 30 years of age. Yet more than half of…

I am writing in response to a letter to the editors written by Drs. Cohen and Mariwalla in the September 2013 JDD entitled “Combining Fillers and Neuromodulators in the Same…

INTRODUCTIONThe role of genetics in the development of psoriasis has been recognized for more than six decades.1 Psoriasis harbors a significant heritable component that is wellestablished, and a family history…

INTRODUCTION Skin and soft tissue infections (SSTIs) are generally uncomplicated at the time of initial presentation. However, these infections can worsen quickly when there are delays in presentation and treatment.…

INTRODUCTIONSpironolactone was developed as a mineralocorticoid receptor antagonist following the observation that spirolactones block the effect of mineralocorticoids in the late 1950’s. The resulting increase in salt and water excretion…

INTRODUCTION Our circadian rhythm is an endogenous timing system generated from the body’s central pacemaker, the suprachiasmatic nucleus (SCN). Located in the hypothalamus and superior to the optic chiasm, its…

INTRODUCTIONAcne is a common condition, which affects most people at some point in their lifetime, including approximately 85% of adolescents.1 In addition to physical effects of acne, such as potential…

INTRODUCTIONOnychomycosis is a nail disease, which affects a high percentage of adult population and presents many difficulties in treatment management.1-3 The therapy consists mainly in broad-spectrum antimycotic agents administered via…

INTRODUCTION Polypodium leucotomos is a tropical fern of the Polypodiaceae family native to Central and South America. Polypodium leucotomos extract (PLE; Fernblock®, Ferndale Laboratories, Ferndale, Michigan, USA) is a polyphenol-enriched…

INTRODUCTIONActinic keratosis (AK) is considered by some as the earliest stage of squamous-cell carcinoma. It is capable of progressing to in situ or invasive squamous-cell carcinoma, and is prevalent in…

INTRODUCTIONTinea pedis is the most commonly encountered superficial cutaneous fungal infection in humans. In the United States, the highly contagious Trichophyton rubrum and Trichophyton mentagrophytes Var interdigitale are recognized as…

INTRODUCTION Actinic keratosis (AK) is one of the most common skin conditions seen in dermatological practice.1 From 2000 to 2003, there were an estimated 5.2 million physician visits annually in…