To the Editor,Vitiligo, a chronic autoimmune condition characterized by loss of melanocytes and resultant skin depigmentation, is associated with reduced quality of life, and increased risks of psychiatric comorbidities such…
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INTRODUCTIONHidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by painful nodules, abscesses, and sinus tracts. Beyond cutaneous symptoms, HS is associated with increased risk of metabolic and cardiovascular…
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INTRODUCTIONLichen planus pigmentosus (LPP) is a rare variant of lichen planus (LP) characterized by persistent dark brown, black, or slate gray coalescing macules primarily affecting sun-exposed areas, including the face,…
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INTRODUCTIONNearly 500,000 individuals seek care for burns yearly in the United States, with 40,000 requiring inpatient care and over 3,000 dying from burn injuries yearly.1 An average of 308 burn…
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INTRODUCTIONThe under-eye region remains one of the most prominent cosmetic concerns due to its thin skin and visibility.1 Periorbital hyperpigmentation, often referred to as dark circles, is a multifactorial condition…
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INTRODUCTIONPsoriasis is driven by proinflammatory cytokines, including interleukin (IL) 17, IL-23, and tumor necrosis factor alpha (TNF-α), resulting in keratinocyte hyperproliferation.1 Several biologic therapies that treat moderate-to-severe psoriasis target TNF-α…
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INTRODUCTIONGranuloma annulare (GA), initially identified as a "ringed eruption of the fingers," is a benign and self-limiting inflammatory skin disorder characterized by granuloma formation in the dermis.1 Its incidence is…
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INTRODUCTIONAcne vulgaris is an inflammatory skin condition that affects 9.4% of the global population.1 Acne is most common during adolescence but can also develop or persist into adulthood.2 Both sexes…
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INTRODUCTIONDespite the growing use of energy-based devices (EBDs) in dermatology, there remains a lack of structured guidance for clinicians on combining EBDs with skin care in acne and post-acne sequelae…
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INTRODUCTIONMachine learning (ML), a subset of artificial intelligence (AI), is a computational approach that utilizes input data to achieve specific goals without relying on explicitly programmed instructions.1 Large language models…
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INTRODUCTIONPsoriasis is a chronic, immune-mediated inflammatory skin disease affecting more than 125 million individuals worldwide.1-3 At the cellular level, aberrant activation of inflammatory pathways triggers keratinocyte hyperproliferation, resulting in the…
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