INTRODUCTIONRetrospective analyses of clinical trial research over the last two decades have revealed that minority enrollment is lacking across all medical specialties, and efforts to increase representation have historically been…
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INTRODUCTIONDominant dystrophic epidermolysis bullosa (DDEB) is a hereditary genetic disorder with a mutation of the type VII collagen gene (COL7A1), resulting in a defect of anchoring collagen VII (Col VII),…
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INTRODUCTIONAcrodermatitis continua of Hallopeau (ACH) is a rare, localized variant of pustular psoriasis. Fewer than 200 cases have been reported in the literature. It is characterized by recurrent, tender, sterile…
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INTRODUCTIONThe aging process is complex, influenced by a dynamic interplay of external (lifestyle and environment) and internal (genetics) factors. Changes such as bone resorption, fat pad depletion, muscle atrophy, and…
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INTRODUCTIONChronic pruritus is a commonly underestimated comorbidity in type 2 diabetes mellitus (T2DM) patients, affecting between 18.4% to 27.5% of diabetics.1 Glucagon-like peptide-1 (GLP-1) agonists have reportedly decreased itch in…
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INTRODUCTIONStandards in wellness and aesthetics have evolved over time, yet the desire to preserve youthful skin remains a universal priority shaped by biological and evolutionary factors.1 Regenerative dermatology is an…
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INTRODUCTIONMelanin provides pigmentation to skin, hair, and eyes and protects epidermal cells by absorbing harmful ultraviolet (UV) rays. Hyperpigmentation results from excess, cumulative melanin triggered by extrinsic aggressors such as…
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INTRODUCTIONGlucagon-like peptide-1 (GLP-1) receptor agonists (RAs) are a class of medications that have been widely used for the control of Type 2 Diabetes Mellitus (T2DM).1 A GLP-1 RA stimulates insulin…
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INTRODUCTIONOnychomycosis, a chronic fungal infection of the nail plate or bed, affects up to 14% of individuals in North America and is the most commonly diagnosed nail disorder in the…
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INTRODUCTIONThe number of aesthetic procedures performed has risen sharply in recent years, increasing 14% from 2019 through 2022. This change is primarily due to a 23% increase in non-surgical aesthetic…
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INTRODUCTIONMelasma is a chronic hyperpigmentation disorder that affects approximately 1% of the general population and up to 1 in 2.5 people in high-risk groups and poses a major therapeutic challenge…
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INTRODUCTIONPigmentary disorders (particularly melasma, postinflammatory hyperpigmentation, and solar lentigines) are among the most common skin disorders, impacting patient quality of life, perception by others, and even self-perception.1,2 Hyperpigmentation results from…
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