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Dec 10
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From DNA Repair to Proteome Protection: New Molecular Insights for Preventing Non-Melanoma Skin Cancers and Skin Aging

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INTRODUCTIONNon-melanoma skin cancers (NMSC) are the most common cancer worldwide and pose a significant and increasing burden on health care resources, with an estimated cost of $650 million and 2,200…
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Dec 10
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In Vivo Efficacy of Nano Hyaluronan-Conjugated Cisplatin for Treatment of Murine Melanoma

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INTRODUCTIONMelanoma is a deadly skin cancer, killing more than 9,000 Americans in 2012. Incidence is rising rapidly, to the point where 1 in 50 Americans will develop melanoma.1 Stage at…
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Dec 10
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The “Smile-and-Fill” Injection Technique: A Dynamic Approach to Midface Volumization

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INTRODUCTIONInjectable poly-L-lactic acid (PLLA) is a biodegradable, biocompatible, synthetic polymer that acts as a scaffold to promote collagen formation.1 It is FDA-approved for the correction of facial lipoatrophy in patients…
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Dec 10
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Selective Radiofrequency Therapy as a Non-Invasive Approach for Contactless Body Contouring and Circumferential Reduction

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INTRODUCTIONExcessive fat is not only cosmetic but also an overall health problem. People who exceed their ideal body weight by more than 20% have an increased risk of type 2…
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Dec 10
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A Preliminary Study on the Safety and Efficacy of a Novel Fractional CO2 Laser With Synchronous Radiofrequency Delivery

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INTRODUCTION AND BACKGROUNDCarbon dioxide (CO2) laser skin resurfacing has been the “gold standard” for cutaneous facial resurfacing of photo-damaged skin since its emergence in the marketplace in the mid-1990s.1-4 Fully…
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Dec 10
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Thanaka: Traditional Burmese Sun Protection

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INTRODUCTION Limonia acidissima or Hesperethusa crenulata is a common tree in Southeast Asia. It is indigenous to the Republic of Myanmar (formerly Burma) as well as India, Sri Lanka, Java,…
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Dec 10
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An Experimental Double-Blind Irradiation Study of a Novel Topical Product (TPF 50) Compared to Other Topical Products With DNA Repair Enzymes, Antioxidants, and Growth Factors With Sunscreens: Implications for Preventing Skin Aging and Cancer

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INTRODUCTIONThe exposure of human skin to solar ultraviolet radiation (UVR) results in the formation of DNA and protein photolesions that can give rise to photoaging and non-melanoma skin cancers (NMSC).1-3…
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Dec 10
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Efficacy and Safety of Ivermectin 1% Cream in Treatment of Papulopustular Rosacea: Results of Two Randomized, Double-Blind, Vehicle-Controlled Pivotal Studies

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INTRODUCTION Papulopustular rosacea (PPR) is a chronic inflammatory disorder characterized by facial papules, pustules, and persistent erythema.1 It is highly prevalent and associated with adverse impact on quality of life…
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Dec 10
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Clinical Effects of a Novel Topical Composition on Persistent Redness Observed in Patients Who Had Been Successfully Treated With Topical or Oral Therapy for Papulopustular Rosacea

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INTRODUCTION Rosacea is a common disorder affecting 16 million people in the US alone.1 Despite earlier beliefs that rosacea was primarily a disease of light-skinned Caucasian, middle-aged women, we now…
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Dec 10
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Development of a New Patient-Reported Outcome Measure for Facial Acne: The Acne Symptom and Impact Scale (ASIS)

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INTRODUCTIONOutcomes in dermatology have traditionally been measured via clinician assessment. However, the patient’s perspective is increasingly recognized as valuable in externally visible skin diseases, as these conditions substantially impact health-related…
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Dec 10
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Biologic Therapy in Erythrodermic and Pustular Psoriasis

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INTRODUCTIONBiologic medications have been thoroughly tested in clinical trials and have well documented efficacy in the treatment of chronic plaque psoriasis. However, there is less data for use in other…
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Dec 10
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Riehl Melanosis Treated Successfully With Q-switch Nd:YAG Laser

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INTRODUCTIONRiehl melanosis is a rare cause of skin hyperpigmentation that typically occurs on the face and neck and is characterized by the rapid onset of gray-brown reticular pigmentation. The condition…
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