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Dec 10
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Combination Use of Ustekinumab With Other Systemic Therapies: A Retrospective Study in a Tertiary Referral Center

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INTRODUCTION Psoriasis is a chronic inflammatory condition affecting 3% of the United States population.1 While most cases are mild and are successfully managed with topical medications, 17% of patients have…
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Dec 10
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Nutritional Clinical Studies in Dermatology

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INTRODUCTION The structural integrity, functional capacity, and regenerative potential of the human skin are known to be influenced, to a variable extent, by a plethora of factors, which thus greatly…
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Dec 10
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Immune Response to Pneumococcus and Tetanus Toxoid in Patients With Moderate-to-Severe Psoriasis Following Long-Term Ustekinumab Use

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INTRODUCTION Ustekinumab (Stelara® Janssen Biotech, Inc., Horsham,PA), a human, monoclonal antibody that binds the shared p40 subunit of interleukin (IL)-12 and IL-23, is approved for the treatment of moderate-to-severe chronic…
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Dec 10
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Curcumin: A Novel Treatment for Skin-Related Disorders

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INTRODUCTION Turmeric is a spice derived from the plant Curcuma Longa, used for centuries in food coloring, cooking, cosmetics, and as a medicinal remedy in the Ayurvedic system of medicine.…
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Dec 10
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Purpura and Fillers: A Review of Pre-Procedural, Intra-Procedural, and Post-Procedural Considerations

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INTRODUCTION With the continuing rise in the use of injectable fillers,patients have become more attuned to the potential complications and side effects. Purpura or bruising is an unwanted side effect…
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Dec 10
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Pimecrolimus Cream and Tacrolimus Ointment in the Treatment of Atopic Dermatitis: A Pilot Study on Patient Preference

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INTRODUCTION Atopic dermatitis is a chronic inflammatory skin disorder associated with considerable disease burden due to repeated episodes of clinical exacerbations and remissions.It follows that atopic patients desire a topical…
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Dec 10
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Efficacy of Combination of Glycolic Acid Peeling With Topical Regimen in Treatment of Melasma

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INTRODUCTION Melasma is a term derived from the Greek word “ melas” meaning black. Melasma is an acquired light or dark brown hyperpigmentation that commonly occurs on the sun exposed…
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Dec 10
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Valrubicin Activates PKCα in Keratinocytes: A Conceivable Mode of Action in Treating Hyper-Proliferative Skin Diseases

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INTRODUCTION Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a semisynthetic anthracycline originally developed from doxorubicin as an anti-cancer drug and currently approved as Valstarâ„¢ (Endo Pharmaceuticals, Lexington, MA) for the treatment of bladder cancer.1,2…
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Dec 10
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Focal Acne Scar Treatment (FAST), a New Approach to Atrophic Acne Scars: A Case Series

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INTRODUCTION Acne is a very common condition that has been reported to affect as many as 80% of adolescents and young adults. The incidence of acne scarring in the general…
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Dec 10
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Etanercept Urticaria in a Patient With Psoriasis Desensitized Using a New Method

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INTRODUCTION Etanercept (Enbrel) is a fusion protein, which is FDA-approved for treatment of moderate to severe rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, moderate to severe plaque psoriasis in adults over…
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Dec 10
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Minimizing Skin Cancer Surgical Scars Using Ablative Fractional Er:Yag Laser Treatment

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INTRODUCTION A short-pulsed Er:YAG laser emits 2940-nm energy which is absorbed 12 to 18 times more efficiently by superficial aqueous tissue than the 10,600-nm energy of the CO2 laser.1 Tissue…
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Dec 10
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A Novel Anti-Inflammatory in Treatment of Acne Vulgaris: The Pseudopterosins

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INTRODUCTION Marine gorgonian organisms are a prolific source of novel biologically active products called the pseudopterosins, which exhibit a range of biomedical activities. For decades, extensive research on the psedopterosins…
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