INTRODUCTIONOral isotretinoin is highly effective for the treatment of severe and recalcitrant acne vulgaris (AV), especially in patients with nodulocystic disease.1-4 Almost all patients treated with oral isotretinoin develop dose-dependent…

INTRODUCTION Acne is a common skin disease characterized by comedones, papules, pustules, nodules and cysts usually on the face, chest, and back. Although most acne studies focus on facial acne,…

INTRODUCTIONAs early as the 1960s, topical tretinoin demonstrated clinical potential in a variety of skin disorders, including acne, actinic keratoses, other hyperkeratotic conditions, and antitumor effects in a number of…

INTRODUCTION Benzoyl peroxide (BPO) is a cornerstone of acne therapy that is often used in combination with a topical antibiotic and/or a retinoid. The use of varying concentrations of BPO…

INTRODUCTIONRosacea is a common skin disorder estimated to affect 16 million Americans.1 Although it is usually observed in patients with light skin phototypes, rosacea has also been diagnosed in patients…

INTRODUCTION Treatment guidelines for moderate to severe acne recommend early initiation of therapy with topical retinoids and oral antibiotics (with or without the use of benzoyl peroxide).1,2 Doxycycline and minocycline,…

INTRODUCTIONRosacea is a chronic cutaneous disorder that is usually found on the face. The disorder is most commonly characterized by flushing, erythema, telangiectasia, edema, papules, and pustules.1 The cause of…

INTRODUCTION Other than visual inspection with the naked eye, the dermatologist’s microscope represents the single most important tool in diagnosing and curing skin diseases. A large number of microscopic techniques…

INTRODUCTIONBullous pemphigoid (BP) is a potentially fatal autoimmune blistering disease that typically affects the elderly, but has also been reported in children.1,2 Bullous pemphigoid usually manifests as tense subepidermal blisters.…

INTRODUCTION Toxic epidermal necrolysis (TEN) is a rare, life-threatening blistering skin condition that is generally caused by exposure to certain high-risk medications.1 Patients typically present with fever, sore throat, and…

INTRODUCTIONVitiligo is a condition characterized by the autoimmune destruction of melanocytes, resulting in loss of pigmentation. This disease affects 1-2% of the world’s population.1 Many have poor results after treatment…

INTRODUCTION Erythema multiforme (EM) is one of the most serious dermatologic diseases. When it is minor, it may be uncomfortable and unsightly. When it is major, it may be life…