PSORIASIS Phase II Randomized Double Blinded Placebo Controlled, Multiple-dose Regimen Study to Assess the Rate of Histological Clearance and Effect on Molecular Pathways as Well as on Biomarkers of 12…

INTRODUCTION Hyperpigmentary disorders of the skin such as melasma, age spots, and solar lentigines result from excessive epidermal melanin synthesized by cutaneous melanocytes.1 Thus, the unique biochemical pathway of melanogenesis…

INTRODUCTION Enfuvirtide, the prototype for a novel class of antiretroviral (ARV) agents deemed to be fusion protein inhibitors, is a prescription drug used for the treatment of human immunodeficiency virus…

INTRODUCTIONOf all the procedures that the average dermatologist performs today, none is more common than the skin biopsy. Although the premise behind local anesthesia is to reduce the pain and…

INTRODUCTIONProton pump inhibitors (PPIs) are the most potent gastric acid–suppressing agents used for preventing nonsteroidal anti-inflammatory drug (NSAID)–induced ulceration and for treating peptic ulcers and other acid-related conditions.1,2 The first…

INTRODUCTION The study of percutaneous absorption (PA) of substances is relevant to the fields of dermatopharmacology (such as in the cases of drug delivery methods and chemical warfare) and occupational…

INTRODUCTION Vitiligo is a common, idiopathic, acquired, depigmenting disease characterized by loss of normal melanin pigments in the skin. It affects 1% to 2% of the general population without sex…

Dr. Sherry Hsiung is the Director of Mohs Micrographic and Dermatologic Surgery at the Skin Institute of New York. She attended the Massachusetts Institute of Technology for her undergraduate studies…

The future is bright for devices in dermatology. The advances made recently in the use of devices for diagnosis and treatment of serious disorders, such as melanoma and other forms…

Pseudoporphyria describes a photodistributed bullous disease that shares clinical and histologic features with porphyria cutanea tarda (PCT) yet has more benign cutaneous findings and normal urine porphyrin levels. The treatment…

INTRODUCTIONProcedural treatments for rhytides, photoaging, and acne scars have ranged from aggressive and highly effective to conservative with minimal efficacy. Traditional or standard ablative laser skin resurfacing (LSR) with carbon…