INTRODUCTION By 1970, systemic corticosteroids, the mainstay therapy of patients with pemphigus vulgaris, had reduced the disease's mortality rate from nearly 100% to approximately 24%.1 The addition of “adjuvant,” corticosteroid-sparing…
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INTRODUCTION Over the past ten years, several biologic agents have been marketed following randomized controlled trials in patients with psoriasis for the indication of plaque psoriasis and/or psoriatic arthritis1,2 for…
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INTRODUCTION Rosacea is a chronic inflammatory facial dermatosis that is typically characterized by a pattern of unpredictable exacerbations and remissions. The highest incidence of rosacea occurs in people of Celtic…
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INTRODUCTION Discoid lupus erythematosus (DLE) is a chronic inflammatory disorder mediated by Th (helper)-1 cells.1 Apremilast blocks the degradation of cyclic adenosine monophosphate (cAMP) via inhibition of the phosphodiesterase (PDE)…
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INTRODUCTION Warts are a common viral infection affecting an estimated 20% of children.1 Therapy for treatment-resistant warts with squaric acid dibutyl ester (SADBE) in acetone, consists of sensitizing with 1%…
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BACKGROUND JFAP Miller discovered the thymic education of T-cell clones in 1961. In 1962, the British leprologists classified leprosy according to the thymus as intact cell-mediated immunity (CMI) tuberculoid and…
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CASE REPORT A white female, aged 22 years, with severe pustular psoriasis and psoriatic arthritis since the age of 14 years had recalcitrant disease and presented for further treatment options.…
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The Henry Ford Hospital Department of Dermatology Residency Program has trained 287 dermatologists in its 59 years of existence. With offices both in urban Detroit and the surrounding metro area,…
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INTRODUCTION This chart summarizes clinical presentations, common locations, and histopathological findings of adnexal tumors from follicular, sebaceous, and eccrine origins. The last column summarizes associations with genetic syndromes and other…
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INTRODUCTION An African-American male, aged 60 years, presented with a 2-month history of asymptomatic nodules on his buttocks and thighs. On examination, there were 5 firm, nontender, subcutanteous nodules measuring…
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Evidence for Supplement Use in Atopic DermatitisINTRODUCTION As the prevalence of atopic dermatitis increases, so does interest in “natural” treatment options as well as prescription medications to address this chronic…
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Watson's Generic Lidoderm® Receives FDA Approval Watson Laboratories, Inc., a subsidiary of Watson Pharmaceuticals, Inc. has announced that it has received final approval from the FDA on its Abbreviated New…
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