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Dec 10
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Sarcoidosis as an Adverse Effect of Tumor Necrosis Factor Inhibitors

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INTRODUCTIONTumor necrosis factor (TNF) inhibitors are a relatively new treatment used for a wide variety of inflammatory skin diseases. As their use increases, the prevalence of rare adverse events also…
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Dec 10
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Improved Texture and Appearance of Human Facial Skin After Daily Topical Application of Barley Produced, Synthetic, Human-like Epidermal Growth Factor (EGF) Serum

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INTRODUCTION Present in a wide variety of tissues and fluids, epidermal growth factor protein (EGF) acts on a subset of the tyrosine kinase receptor family.1 Epidermal growth factor serves primarily…
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Dec 10
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Where Does Rituximab Fit in the Treatment of Autoimmune Mucocutaneous Blistering Skin Disease?

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INTRODUCTION Scientific evidence supporting the optimal treatment for autoimmune mucocutaneous blistering diseases (AMBD) today has not been established.1 High dose systemic corticosteroids are often cited as first line therapy. Because…
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Dec 10
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Lessons of Leprosy: The Emergence of TH17 Cytokines During Type II Reactions (ENL) Is Teaching Us About T-cell Plasticity

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INTRODUCTION Frank Macfarlane Burnet won the Nobel Prize for the clonal selection theory of immunity in 1960. 1 In 1961, Miller published evidence that these lymphocyte "clones" were educated in…
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Dec 10
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A Comparison of Physicochemical Properties of a Selection of Modern Moisturizers: Hydrophilic Index and pH

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INTRODUCTIONAvast array of choices are available for skin moisturizers, making the selection process an overwhelming task for both consumers and health care practitioners. Despite this problem, few studies have compared…
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Dec 10
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Biophysical Evaluation of Fractional Laser Skin Resurfacing With an Er:YSGG Laser Device in Japanese Skin

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INTRODUCTION The fractional laser skin resurfacing (FLSR) system is a new skin treatment concept using multiple microscopic laser beams.1,2 The two main types of FLSR systems currently available are ablative…
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Dec 10
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Fitzpatrick Skin Types and Clindamycin Phosphate 1.2%/Benzoyl Peroxide Gel: Efficacy and Tolerability of Treatment in Moderate to Severe Acne

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People of color represent the fastest-growing segment of the US population. In 2000, they represented less than one-third of the nation's total population. By 2050, U.S. Census estimates suggest that…
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Dec 10
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A New Simple, Safe, and Easy Solution for Upper Lip Dermabrasion

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INTRODUCTION Manual dermabrasion compares favorably to mechanical dermabrasion and laser resurfacing due to its safety, minimal cost, ease of use and emancipation from the need to depend on cumbersome, complex…
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Dec 10
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RESIDENT ROUNDS: PART I
Program Spotlight: Department of Dermatology,Oregon Health & Science University

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Since 1922, the Oregon Health & Science University (OHSU) Department of Dermatology has enjoyed a rich tradition of leadership and innovation in cutaneous medicine. Our current team of 20 clinical…
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Dec 10
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Infliximab (Remicade) and Increased Incidence of Development of Basal Cell Carcinoma

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INTRODUCTION It has been well documented in the literature that immunosuppression is a risk factor for the development of non-melanoma skin cancers (NMSC). Therefore, it is not surprising that patients…
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Dec 10
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RESIDENT ROUNDS: PART II
Contact Allergens Relevant to Dermatitis in Special Locations

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INTRODUCTIONThis study guide is intended to help dermatology residents prepare for contact dermatitis questions on ABD in-service and board exams. Additionally, it may serve as a useful tool in a…
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Dec 10
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Treatment of Mild to Moderate Facial Melasma With the Lumixyl Topical Brightening System

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INTRODUCTIONMelasma is a common cutaneous disorder that presents as patches of darker pigmentation on the cheeks, forehead, upper-lip, nose, and chin.1 Melasma most commonly affects females of Asian and Hispanic…
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