PSORIASISPhase II Randomized Double Blinded Placebo Controlled, Multiple-dose Regimen Study to Assess the Rate of Histological Clearance and Effect on Molecular Pathways as Well as on Biomarkers of 12 Months…

BACKGROUNDBotanicals have dominated pharmacopoeias across the globe for thousands of years and continue to serve as a valuable source of therapeutic compounds because of their vast biosynthetic capacity.1 They are…

INTRODUCTIONSorafenib (SO) and sunitinib (SU) are small molecule inhibitors with various targets that have shown benefits in various malignancies, significantly improving progression- free survival and overall survival, with reduced adverse…

INTRODUCTIONCommon warts are caused by the human papillomavirus (HPV). They affect 2% to 20% of school-aged children.1 This infection can cause physical and emotional distress in patients.2 There are different…

INTRODUCTION Tinea inguinalis is a mycotic infection of the inguinal folds that usually occurs in young men living in warm, humid climates. Trichophyton rubrum, Epidermophyton floccosum, and Trichophyton mentagrophytes are…

INTRODUCTIONPsoriasis verrucosa is a peculiar clinical form of psoriasis characterized by very thick and hard scales adherent to erythematous lesions, producing a wartlike appearance.1 The case of a Japanese patient…

Dr. Ronald L. Moy is a leading cosmetic and dermatologic surgeon practicing in Los Angeles, California. He is board certified in dermatology and cosmetic surgery, and specializes in Mohs micrographic…

Dermatologists have a rich history of thinking outside the box. We are especially adventurous as compared to our medical peers when it comes to trying novel or off-label therapies for…

The recent article by de Oliveira et al1 was highly interesting and thought provoking. Interestingly, the past few years have seen the identification of a number of new inhibitors of…

INTRODUCTIONPathophysiology of AK: Progression from Normal Skin to Keratinocyte Cancers Actinic keratoses (AKs) are intraepidermal cutaneous areas of atypical squamous transformation that develop as a result of excessive exposure to…

INTRODUCTIONCurrent therapies for acne include topical treatments, systemic antibiotics, hormonal agents, isotretinoin, complementary therapies, and other miscellaneous treatments.1 Excluding benzoyl peroxide preparations, regimens containing salicylic acid (SA) as the active…

INTRODUCTIONRosacea is a common, chronic dermatologic condition that most commonly affects sun-sensitive, pale-skinned individuals of Northern or Eastern European descent and those of Celtic heritage.1-3There is no clearly identified cause…