INTRODUCTIONTherapy of actinic keratosis (AK) using imiquimod 5% cream (Aldara, MEDA Pharmaceuticals, Somerset, NJ) was approved in the United States and European Union in 2005 and 2006, respectively. Despite the…

INTRODUCTION Hispanics represent the largest and fastest growing minority group in the United States. Over the past decade the Hispanic population has increased by 43% and now accounts for 16.3%…

INTRODUCTIONHuman cutaneous malignant melanoma is one of the most resistant tumors to treat, being responsible for 75% of skin cancer-related deaths.1Despite improvements in the management of this tumor, its treatment…

INTRODUCTIONDiscrete actinic keratoses (AKs) may be treated by cryosurgery with liquid nitrogen, curettage with electrodessication, topical creams (imiquimod, 5-fluorouracil, diclofenac), or surgery; however, targeted therapeutic modalities are not as effective…

INTRODUCTIONActinic keratosis (AK) is a chronic disease and part of a biologic continuum between photodamaged skin and invasive squamous cell carcinoma (SCC).1 Long-term management is required for AK because photodamage…

INTRODUCTIONTumor necrosis factor (TNF) inhibitors are a relatively new treatment used for a wide variety of inflammatory skin diseases. As their use increases, the prevalence of rare adverse events also…

INTRODUCTION Present in a wide variety of tissues and fluids, epidermal growth factor protein (EGF) acts on a subset of the tyrosine kinase receptor family.1 Epidermal growth factor serves primarily…

INTRODUCTION Scientific evidence supporting the optimal treatment for autoimmune mucocutaneous blistering diseases (AMBD) today has not been established.1 High dose systemic corticosteroids are often cited as first line therapy. Because…

INTRODUCTION Frank Macfarlane Burnet won the Nobel Prize for the clonal selection theory of immunity in 1960. 1 In 1961, Miller published evidence that these lymphocyte "clones" were educated in…

INTRODUCTIONAvast array of choices are available for skin moisturizers, making the selection process an overwhelming task for both consumers and health care practitioners. Despite this problem, few studies have compared…

INTRODUCTION The fractional laser skin resurfacing (FLSR) system is a new skin treatment concept using multiple microscopic laser beams.1,2 The two main types of FLSR systems currently available are ablative…

People of color represent the fastest-growing segment of the US population. In 2000, they represented less than one-third of the nation's total population. By 2050, U.S. Census estimates suggest that…