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Dec 10
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A Randomized, Double-Blind, Vehicle-Controlled Efficacy and Safety Study of Naftifine 2% Cream in the Treatment of Tinea Pedis

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INTRODUCTION Tinea pedis, the proverbial "athlete's foot," is the most common superficial fungal infection, estimated to be present at any one time in 15-20 percent of the US and European…
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Dec 10
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A Review of the Chemopreventative Effects of Oral Retinoids for Internal Neoplasms

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INTRODUCTION Recent population-based studies have suggested that patients with psoriasis are at higher risk for development of systemic malignancies.1 In addition, other than oral retinoids, all systemic therapy used to…
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Dec 10
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Imiquimod: A Review of Off-Label Clinical Applications

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INTRODUCTION Toll-like receptors (TLRs) are located on antigen presenting cells of the innate immune system such as macrophages and dendritic cells.1 TLRs are links between the innate immune response and…
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Dec 10
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Hair Regrowth Following a Wnt- and Follistatin- Containing Treatment: Safety and Efficacy in a First-in-Man Phase 1 Clinical Trial

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INTRODUCTIONAndrogenetic alopecia is a widespread cosmetic and medical disorder for which there exist few treatment options. The current therapeutic strategies including surgical, pharmaceutical, and cosmetic interventions are limited in approach…
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Dec 10
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Q-Switched Laser Treatment of Amiodarone Pigmentation

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INTRODUCTIONDrug-induced cutaneous pigmentation has been described resulting from a number of medications, but most commonly from minocycline and amiodarone. 1-28 Affected skin typically develops a slate-gray pigmentation. Histopathologic evaluation of…
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Dec 10
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Multiple Facial Burns With the New Thermage CPT System

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INTRODUCTIONSince its approval in 2002, the use of radiofrequency for tightening the skin in the cosmetic dermatology realm has seen several innovations in technology.1,2 Many companies have developed devices with…
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Dec 10
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Mohs Micrographic Surgery for the Treatment of Cutaneous Lymphadenoma

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INTRODUCTION Cutaneous lymphadenoma (CL) is a benign neoplasm commonly presenting on the head and neck of young and middle-aged adults as a small, solitary nodule.1-3 The histogenesis of these tumors…
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Dec 10
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Bullous Pemphigoid After Herpes Zoster Vaccine Administration: Association or Coincidence?

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CASE REPORT A 72-year-old man of Indian descent received a single dose injection of zoster vaccine (Zostavax vaccine) in October 2008 when traveling in India. Two weeks later he developed…
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Dec 10
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Chloracne-Like Drug Eruption Associated With Sorafenib

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INTRODUCTIONSorafenib is a multikinase inhibitor that has been recently been approved by the FDA for the treatment of metastatic renal cell carcinoma.1 Sorafenib works by inhibiting tyrosine and serine/threonine kinases…
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Dec 10
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Resident Rounds Part I: Program Spotlight – The University of Louisville Dermatology Residency Training Program

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CASE REPORT The University of Louisville Division of Dermatology is located in Louisville, Kentucky. The Division consists of four full-time faculty and over 30 faculty and volunteer clinicians, headed by…
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Dec 10
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Resident Rounds Part II:Highlights of Common Autoimmune Connective Tissue Diseases

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Understanding the common variables and differences with autoimmune connective tissue diseases can be a challenge. This table highlights the clinical, pathological, laboratory and treatment differences for residents and practicing dermatologists.DisclosuresThe…
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Dec 10
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Resident Rounds. Part III: Erosive and Desquamative Syphilis Associated With Mucositis in the Setting of Acquired Immune Deficiency Syndrome

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CASE REPORTA 49-year-old man with an eight-year history of HIV was admitted to the hospital because of fever, chills, and a painful, desquamating eruption. The eruption had begun two months…
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