use of many potentially effective drugs whose use has, until now, been limited by risks of excessive systemic exposure and associated unwanted adverse effects.
This is truly an advancement in the field of drug designing and targeted delivery that is so close to my heart.
This is truly an advancement in the field of drug designing and targeted delivery that is so close to my heart.
Leon H. Kircik MD
Icahn School of Medicine at Mount Sinai, New York, NY
Indiana University Medical Center, Indianapolis, IN Physicians Skin Care, PLLC, Louisville, KY
DermResearch, PLLC, Louisville, KY
Skin Sciences, PLLC, Louisville, KY
DISCLOSURE Leon H. Kircik, MD has received compensation for his editorial efforts from JDD and has served as a consultant and advisor for Brickell, Dermira, and Eli Lilly.
REFERENCES
1. Cheruvu HS, Liu X, Grice JE, Roberts MS. Modeling percutaneous absorption for successful drug discovery and development. ExpertOpin Drug Discov. 2020 Oct;15(10):1181-1198.
2. Bodor NB, Buchwald P. Retrometabolism-Based Drug Design and Targeting. In: Burger’s Medicinal Chemistry and Drug Discovery, DJAbraham, Editor. 2003, John Wiley & Sons, Inc.
3. Pariser D. What’s new in the management of hyperhidrosis. In: Fall Clinical Dermatology Conference. 2021. Las Vegas, NV.
4. Yokozeki H, et al. A phase 3, multicenter, randomized, double-blind, vehicle-controlled, parallel-group study of 5% sofpironium bromide(BBI-4000) gel in Japanese patients with primary axillary hyperhidrosis. J Dermatol. 2021;48(3):279-288.
Icahn School of Medicine at Mount Sinai, New York, NY
Indiana University Medical Center, Indianapolis, IN Physicians Skin Care, PLLC, Louisville, KY
DermResearch, PLLC, Louisville, KY
Skin Sciences, PLLC, Louisville, KY
DISCLOSURE Leon H. Kircik, MD has received compensation for his editorial efforts from JDD and has served as a consultant and advisor for Brickell, Dermira, and Eli Lilly.
REFERENCES
1. Cheruvu HS, Liu X, Grice JE, Roberts MS. Modeling percutaneous absorption for successful drug discovery and development. ExpertOpin Drug Discov. 2020 Oct;15(10):1181-1198.
2. Bodor NB, Buchwald P. Retrometabolism-Based Drug Design and Targeting. In: Burger’s Medicinal Chemistry and Drug Discovery, DJAbraham, Editor. 2003, John Wiley & Sons, Inc.
3. Pariser D. What’s new in the management of hyperhidrosis. In: Fall Clinical Dermatology Conference. 2021. Las Vegas, NV.
4. Yokozeki H, et al. A phase 3, multicenter, randomized, double-blind, vehicle-controlled, parallel-group study of 5% sofpironium bromide(BBI-4000) gel in Japanese patients with primary axillary hyperhidrosis. J Dermatol. 2021;48(3):279-288.
