disruption or discontinuation, which is paramount to improved outcomes. Such treatment must be efficacious without adding additional harm; therefore, broad immunosuppression, including systemic corticosteroids, should be avoided when possible.
For each cirAE, specific treatment approaches will be discussed, but gentle skin care should be reviewed with all patients. This includes gentle cleansing with soap and water as well as daily use of hydrating emollients such as lotions, creams, or ointments based on the extent of xerosis as well as personal preference. Hygiene and cleaning products should be fragrance-free, and patients should avoid introducing new products into their routines whenever possible. As with gentle skin care, recommendations regarding the decision to discontinue or interrupt immunotherapy are fairly standardized. Such consideration is taken in patients with grade 3 reactions, during which immunotherapy can be held while addressing the cirAE. This warrants consideration of same-day consultation with a dermatologist when assistance is desired. When the cutaneous reaction has been addressed, immunotherapy may be restarted
