Statistical methods included descriptive statistics for variables, paired t-test or Wilcoxon signed-rank test if t-test normality fails, and z-test for percentage of participants improved or with favorable responses on the questionnaire.
RESULTS
A total of 30 healthy male and female patients participated in the study, with participant demographics shown in Table 1.
Effectiveness
Both products significantly improved skin hydration at week 4 vs baseline as demonstrated by corneometer measurements (Figure 1) with a mean difference from baseline of 10.8 for ESM and 6.0 for IRML (P less than of equal to 0.001 for both) at the arm site and 6.6 for ESM and 3.4 for IRML in the leg (P less than of equal to 0.001) for both. However, skin hydration was significantly higher in the ESM-treated areas compared to the IRML at week 4 (P<0.05).
