INDIVIDUAL ARTICLE: Efficacy of a Prebiotic Skincare Regimen on Improving Mild Atopic Dermatitis and Severe Xerosis in Diverse Ethnically Patients

March 2024 | Volume 23 | Issue 3 | SF395747s12 | Copyright © March 2024


Published online March 1, 2024

Hawasatu Dumbuya PhDa, Katharine Podimatis MDa, Delphine Kerob MDb, Zoe Diana Draelos MDc

aLa Roche-Posay Laboratoire Dermatologique, L'Oreal USA, New York, NY
bLa Roche-Posay Laboratoire Dermatologique, L'Oreal, Levallois-Perret, France
cDermatology Consulting Services, PLLC, High Point, NC



by week 10 (Figure 3A). Interestingly, AD patients of color (Fitz IV-VI, n=31) showed earlier reduction in itching sensation with cleanser at week 2, despite experiencing greater sensation at baseline compared to white counterparts (Fitz I-III, n=38) (Figure 3B). These results were consistent with the significant improvement in quality-of-life perceived by all AD subjects (Figure 4A & 4B). Xerosis subjects perceived significant increase in itching sensation with cleanser alone at 2 weeks, reaching complete relief with regimen by week 8 (Figure 3A). Despite experiencing this initial increase in itch sensation, xerosis patients perceived a significant reduction in itching intensity levels with cleanser alone at week 2, and with regimen by week 10 (Figure 3C). Interestingly, xerosis patients of color (Fitz IV-VI, n=25) showed earlier reduction in itching intensity (Figure 3D), while white counterparts (Fitz I-III, n=44) showed greater improvement in quality-of-life with cleanser alone and with regimen overtime (Figure 4A & 4C).