INDIVIDUAL ARTICLE: Atopic Dermatitis Skincare and Impact on Quality of Life for Patients with Skin of Color

March 2024 | Volume 23 | Issue 3 | SF395747s6 | Copyright © March 2024


Published online March 1, 2024

Hawasatu Dumbuya PhDa, Chesahna Kindred MD MBAb, Cheri N. Frey MDc, Zoe Diana Draelos MDd

aLa Roche-Posay Laboratoire Dermatologique, L'Oréal USA, New York, NY
bKindred Hair & Skin Center, Columbia, MaD
cHoward University Dept of Dermatology, Washington, DC
dDermatology Consulting Services, PLLC, High Point, NC

    1. Patel KR, Singam V, Vakharia PP, et al. Measurement properties of three assessments of burden used in atopic dermatitis in adults. Br J Dermatol. 2019;180(5):1083-1089. 
    2. McKenzie C, Silverberg JI. The prevalence and persistence of atopic dermatitis in urban United States children. Ann Allergy Asthma Immunol. 2019;123(2):173-178.e1. 
    3. Silverberg JI, Margolis DJ, Boguniewicz M, et al. Validation of five patient-reported outcomes for atopic dermatitis severity in adults. Br J Dermatol. 2020;182(1):104-111. 
    4. Kaufman BP, Guttman-Yassky E, Alexis AF. Atopic dermatitis in diverse racial and ethnic groups-Variations in epidemiology, genetics, clinical presentation and treatment. Exp Dermatol. 2018;27(4):340-357. 
    5. Leung DY. Atopic dermatitis: Age and race do matter! J Allergy Clin Immunol. 2015;136(5):1265-1267. 
    6. Alexis A, Woolery-Lloyd H, Andriessen A, et al. Insights in skin of color patients with atopic dermatitis and the role of skincare in improving outcomes. J Drugs Dermatol. 2022;21(5):462- 470. 
    7. Brunner PM, Guttman-Yassky E. Racial differences in atopic dermatitis. Ann Allergy Asthma Immunol. 2019;122(5):449-455. 
    8. Margolis DJ, Apter AJ, Gupta J, et al. The persistence of atopic dermatitis and filaggrin (FLG) mutations in a US longitudinal cohort. J Allergy Clin Immunol. 2012;130(4):912-917. 
    9. Abuabara K, You Y, Margolis DJ, et al. Genetic ancestry does not explain increased atopic dermatitis susceptibility or worse disease control among African American subjects in 2 large US cohorts. J Allergy Clin Immunol. 2020;145(1):192-198.e11. 
    10. Hirano SA, Murray SB, Harvey VM. Reporting, representation, and subgroup analysis of race and ethnicity in published clinical trials of atopic dermatitis in the United States between 2000 and 2009. Pediatr Dermatol. 2012;29(6):749-755. 
    11. Chatrath S, Bradley L, Kentosh J. Dermatologic conditions in skin of color compared to white patients: similarities, differences, and special considerations. Arch Dermatol Res. 2023;315(5):1089-1097. 
    12. Sevagamoorthy A, Sockler P, Akoh C, et al. Racial and ethnic diversity of US participants in clinical trials for acne, atopic dermatitis, and psoriasis: a comprehensive review. J Dermatolog Treat. 2022;33(8):3086-3097. 
    13. Alexis AF, Woolery-Lloyd H, Williams K, et al. Racial/ethnic variations in skin barrier: implications for skincare recommendations in skin of color. J Drugs Dermatol. 2021;20(9):932-938. 
    14. Diridollou S, de Rigal J, Querleux B, et al. Comparative study of the hydration of the stratum corneum between four ethnic groups: influence of age. Int J Dermatol. 2007;46 Suppl 1:11- 14. 
    15. Shaw FM, Luk KMH, Chen KH, et al. Racial disparities in the impact of chronic pruritus: A cross-sectional study on quality of life and resource utilization in United States veterans. J Am Acad Dermatol. 2017;77(1):63-69. 
    16. Wan J, Margolis DJ, Mitra N, et al. Racial and Ethnic Differences in Atopic Dermatitis-Related School Absences Among US Children. JAMA Dermatol. 2019;155(8):973-975. 
    17. Wan J, Oganisian A, Spieker AJ, et al. Racial/Ethnic variation in use of ambulatory and emergency care for atopic dermatitis among US children. J Invest Dermatol. 2019;139(9):1906-1913. e1. 
    18. Bell MA, Whang KA, Thomas J, et al. Racial and ethnic disparities in access to emerging and frontline therapies in common dermatological conditions: a cross-sectional study. J Natl Med Assoc. 2020;112(6):650-653. 
    19. Tackett KJ, Jenkins F, Morrell DS, et al. Structural racism and its influence on the severity of atopic dermatitis in African American children. Pediatr Dermatol. 2020;37(1):142-146. 
    20. Silverberg JI, Gelfand JM, Margolis DJ, et al. Atopic dermatitis in US adults: from population to health care utilization. J Allergy Clin Immunol Pract. 2019;7(5):1524-1532.e2. 
    21. Chovatiya R, Begolka WS, Thibau IJ, et al. Financial burden and impact of atopic dermatitis out-of-pocket health care expenses among black individuals in the United States. Arch Dermatol Res. 2022;314(8):739-747. 
    22. Eichenfield LF, Tom WL, Chamlin SL, et al. Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis. J Am Acad Dermatol. 2014;70(2):338-351. 
    23. Eichenfield LF, Tom WL, Berger TG, et al. Guidelines of care for the management of atopic dermatitis: section 2. Management and treatment of atopic dermatitis with topical therapies. J Am Acad Dermatol. 2014;71(1):116-132. 
    24. Simpson EL, Chalmers JR, Hanifin JM, et al. Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention. J Allergy Clin Immunol. 2014;134:818- 23. 
    25. Harcharik S, Emer J. Steroid-sparing properties of emollients in dermatology. Skin Therapy Lett. 2014;19(1):5-10.
    26. van Zuuren EJ, Fedorowicz Z, Christensen R, et al. Emollients and moisturisers for eczema. Cochrane Database Syst Rev. 2017;2(2):CD012119. 
    27. Rerknimitr P, Otsuka A, Nakashima C, et al. Skin barrier function and atopic dermatitis. Curr Derm Rep. 2018;7:209-220. 
    28. Danby SG, Andrew PV, Brown K, et al. An investigation of the skin barrier restoring effects of a cream and lotion containing ceramides in a multi-vesicular emulsion in people with dry, eczema-prone, skin: the RESTORE study phase 2. J Am Acad Dermatol. 2020;83(6):Suppl AB71. 
    29. Strugar TL, Kuo A, Seité S, et al. Connecting the dots: from skin barrier dysfunction to allergic sensitization, and the role of moisturizers in repairing the skin barrier. J Drugs Dermatol. 2019;18(6):581. 
    30. Seite S, Bieber T. Barrier function and microbiotic dysbiosis in atopic dermatitis. Clin Cosmet Investig Dermatol. 2015;8:479- 483. 
    31. Baldwin HE, Bhatia ND, Friedman A, et al. The role of cutaneous microbiota harmony in maintaining a functional skin barrier. J Drugs Dermatol. 2017;16(1):12-18. 
    32. Seite S, Flores GE, Henley JB, et al. Microbiome of affected and unaffected skin of patients with atopic dermatitis before and after emollient treatment. J Drugs Dermatol. 2014;13(11):1365- 1372. 
    33. Gueniche A, Knaudt B, Schuck E, et al. Effects of nonpathogenic gram-negative bacterium Vitreoscilla filiformis lysate on atopic dermatitis: a prospective, randomized, double-blind, placebo-controlled clinical study. Br J Dermatol. 2008;159(6):1357- 1363. 
    34. Seité S, Zelenkova H, Martin R. Clinical efficacy of emollients in atopic dermatitis patients - relationship with the skin microbiota modification. Clin Cosmet Investig Dermatol. 2017;10:25- 33. 
    35. Moreau M, Seité S, Aguilar L, et al. Topical S. aureus - targeting endolysin significantly improves symptoms and QoL in individuals with atopic dermatitis. J Drugs Dermatol. 2021;20(12):1323-1328. 
    36. Zelenkova H, Kerob D, Salah S, et al. Impact of daily use of emollient 'plus' on corticosteroid consumption in patients with atopic dermatitis: An open, randomized controlled study. J Eur Acad Dermatol Venereol. 2023:37 Suppl 5:27-34. 
    37. Magnolo N, Jaenicke T, Tsianakas A, et al. Comparison of different skin care regimens in patients with moderate to severe atopic dermatitis receiving systemic treatment: A randomized controlled trial. J Eur Acad Dermatol Venereol. 2023:37 Suppl 5:18-26. 
    38. Wollenberg A, Kinberger M, Arents B, et al. European guideline (EuroGuiDerm) on atopic eczema: part I - systemic therapy. J Eur Acad Dermatol Venereol. 2022;36(9):1409-1431. 
    39. Wollenberg A, Kinberger M, Arents B, et al. European guideline (EuroGuiDerm) on atopic eczema - part II: non-systemic treatments and treatment recommendations for special AE patient populations. J Eur Acad Dermatol Venereol. 2022;36(11):1904- 1926. 
    40. Crudele J, Kim E, Murray K, et al. The importance of understanding consumer preferences for dermatologist recommended skin cleansing and care products. J Drugs Dermatol. 2019;18(1s):s75-s79.

AUTHOR CORRESPONDENCE

Hawasatu Dumbuya PhD hawasatu.dumbuya@loreal.com