Recently, fractional ablative radiofrequency (RF) technology has become commercially available and is gaining clinical recognition and popularity as novel fractional lasers in procedural dermatology.1,2 When compared to fractional ablative lasers (Er:YAG and CO2), fractional ablative radiofrequency technology to be bipolar or unipolar is still lacking understanding skin interaction and morpho-histology evidence.3,4
In the fractional bipolar RF devices the technology is forming an array of positive and negative charged multielectrod-pins on the surface of the skin. The RF current flows via the skin between the electrode-pins rows. This results in heating the pins to temperature leading to ablation, coagulation/necrosis and sub necrotic tissue zones, while leaving intact or slightly affected zones in between the pins.
In contrast, the Accent XL (Alma Lasers Ltd., Caesarea, Israel) is a novel unipolar RF-based technology, creating fractional ablative micro-plasma perforation on the skin.
Plasma is a partially ionized gas that contains charged carriers (electrons and ions), active radicals and excited molecules.
When a plasma contacts tissue, various effects can be achieved, from vaporization to simple heating of biological tissue. When the plasma interacts with the skin, there is a superficial, microplasma injury (ablative-thermal) of the skin ranging between 150-200 μm in depth and 80-120 μm in width.5
The purpose of this study was to document dose-response skin interaction of a novel unipolar RF micro-plasma technology in animal model through evaluation histology and ultra microstructure trends over time. In addition, the study aimed to suggest new revelation of the technology current clinical application.
Materials & METHODS
Thirty male and female cavies were randomly selected for this study. Cavies weight ranged between 0.25-0.35kg and age between 7-10 years old (Li Tong Li Hua, Beijing animal company, China). Each cavy was fed by group separately to adapt the environment. Animal waiting time for experiments was one week.
The Accent XL (Alma Lasers Ltd.) is a radiofrequency platform operated at a frequency of 40.68 MhZ. The Accent XL RF-based handpiece creates ablative fractional micro-plasma events,