In this issue:
Generalized Pustular Psoriasis: A Contemporary Review of Diagnosis, Pathophysiology, and IL-36 Pathway–Directed Management
Generalized pustular psoriasis (GPP) is a rare, chronic, severe autoinflammatory dermatosis distinguished by abrupt flares of sterile pustulation, systemic inflammation, and substantial morbidity and mortality.1-4 Once viewed as a variant of plaque psoriasis, accumulating epidemiologic, clinical, and mechanistic evidence now establishes GPP as a distinct disease entity with unique diagnostic challenges, extracutaneous manifestations, and therapeutic priorities. Patients may require ...
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Generalized Pustular Psoriasis: A Contemporary Review of Diagnosis, Pathophysiology, and IL-36 Pathway–Directed Management
Generalized pustular psoriasis (GPP) is a rare, chronic, severe autoinflammatory dermatosis distinguished by abrupt flares of sterile pustulation, systemic inflammation, and substantial morbidity and mortality.1-4 Once viewed as a variant of plaque psoriasis, accumulating epidemiologic, clinical, and mechanistic evidence now establishes GPP as a distinct disease entity with unique diagnostic challenges, extracutaneous manifestations, and therapeutic priorities. Patients may require ...
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