Resident Rounds: Part II - Hereditary Syndromes Associated With Increased Risk of Keratinocyte Carcinomas

June 2015 | Volume 14 | Issue 6 | Features | 633 | Copyright © June 2015

Erin X. Wei MD, Jose E. Ollague MD, and Jonathan Weiss MD

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL

Abstract

INTRODUCTION

These tables review the inheritance patterns, involved genes, and clinical findings of the many hereditary syndromes associated with an increased risk of keratinocyte carcinomas. While these genodermatoses present with complex clinical pictures, often affecting multiple organ systems, the identification of an increased risk of skin cancers is crucial. Patient and family education regarding primary prevention, as well as frequent full body skin examinations, can significantly decrease morbidity and improve the prognosis of these patients.
table 1