Amantadine-Induced Livedo Reticularis: A Report of Two Cases
March 2006 | Volume 5 | Issue 3 | Case Reports | 288 | Copyright © March 2006
Benjamin B. Hayes MD PhD, Robert H. Cook-Norris BS, Jami L. Miller MD, Adrian Rodriguez MD, John A. Zic MD
AbstractIn the last several years, amantadine has been increasingly prescribed for akinesia in Parkinsonâ€™s disease and to combat fatigue associated with multiple sclerosis. Amantadine is a well-known medication involved in drug-induced livedo reticularis (LR),1 yet remains under-reported in the English literature. We describe 2 patients with amantadine livedo reticularis: one patient with multiple sclerosis had, previous to this eruption, tolerated 4 years of amantadine therapy without adverse reactions and another patient with Parkinsonâ€™s disease who developed LR 1 month after starting amantadine.