A Practical Algorithm Integrating Skin Care With Nonenergy and Injectable Dermatologic Procedures to Improve Patient Outcomes and Satisfaction

April 2024 | Volume 23 | Issue 4 | 227 | Copyright © April 2024


Published online March 27, 2024

Edward Lain MD FAADa, Anneke Andriessen PhDb, Valeria Barreto Campos MDc, Sabrina Guillen Fabi MD FAAD FAACSd, Lisa Ginn MD FAADe, Ariel Haus MDf, Valerie M. Harvey MDg, Jean-Francois Tremblay MD FRCPCh

aSanova Dermatology, Austin Institute for Clinical Research, Austin, TX 
bRadboud UMC Nijmegen, Andriessen Consultants, Malden, NL
cUniversity of Jundiai, Sao Paulo, Brazil 
dCosmetic Laser Dermatology, San Diego; University of California, San Diego, CA 
eSkin@LRG, Bethesda, MD 
fDr Haus Dermatology, London, England 
gTPMG Hampton Roads Center for Dermatology, Virginia Beach and Newport News, VA
hFunctionalab Group, Dermapure, Project Skin MD, Montreal, Quebec, Canada 



combined with protective measures, such as wearing a wide-brimmed hat and sunglasses, is recommended.4,5,14,15 

Tinted iron oxide sunscreens without a white cast in richly pigmented skin could improve compliance. In addition, using topical technologies that contain ingredients with antioxidants and free radical quenchers may help to prevent dyschromia,14-16 which is a significant concern for those with richly pigmented skin and of Asian descent.14-17 

Injecting fillers sub-dermally with longer, slower injection times may help decrease the risk of dyschromia.17,18 Healthcare providers should be informed on skin thickness variability among facial areas in richly pigmented patients, which affects optimal injection depth.17,18 During the procedure, skin cleansing products are addressed, along with judicious techniques to minimize unintended cutaneous injury or inflammation.   

Clinicians may pretreat patients with products to prevent hyper or hypopigmentation before nonenergy or injectable treatments. However, this recommendation is primarily for patients with richly pigmented skin or those with a history of dyschromia or abnormal scarring.4,5,14-17 Melanocytes are hyper-reactive in richly pigmented skin, leading to more pigment disorders, such as hyper or hypopigmentation, a frequent sequela of inflammatory dermatoses, skin injury, or photodamage.14-17 Pretreatment prevention of hyper or hypopigmentation comprises topical arnica/bromelain or hydroquinone and agents to impact melanogenesis.4,5,14,15 Other options are products containing niacinamide, kojic acid (KA), azelaic acid (AzA), retinoids, and tranexamic acid (TXA). Pretreatment with skin care using a gentle